Lau, K M; Madden, E; Neylan, T C; Seal, K H; Maguen, S
Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors Journal Article
In: Brain Injury, vol. 30, no. 3, pp. 287–294, 2016.
Abstract | BibTeX | Tags: *Afghan Campaign 2001-, *Brain Concussion/di [Diagnosis], *Iraq War, *Veterans/sn [Statistics & Numerical Data], 2003-2011, adult, Brain Concussion/pp [Physiopathology], Brain Concussion/px [Psychology], Cohort Studies, Female, Humans, Injury Severity Score, Male, middle aged, Military personnel, Post-Traumatic/di [Diagnosis], Post-Traumatic/pp [Physiopatholo, Post-Traumatic/px [Psychology], Retrospective Studies, self report, Stress Disorders, UNITED States, United States Department of Veterans Affairs
@article{Lau2016a,
title = {Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors},
author = {Lau, K M and Madden, E and Neylan, T C and Seal, K H and Maguen, S},
year = {2016},
date = {2016-01-01},
journal = {Brain Injury},
volume = {30},
number = {3},
pages = {287--294},
abstract = {OBJECTIVE: To investigate injury severity markers and neurological symptoms associated with clinician-confirmed mild traumatic brain injury (TBI) among Iraq and Afghanistan veterans. SETTING: Department of Veterans Affairs (VA) medical centre and five affiliated community-based outpatient clinics. PARTICIPANTS: Three hundred and fifty Iraq and Afghanistan veterans with positive initial VA TBI screens between 1 April 2007 and 1 June 2010 and clinician-confirmed TBI status by 1 December 2010. METHODS: Retrospective-cohort study of medical record data. Main measures included clinician-confirmed TBI status, injury severity markers (e.g. loss of consciousness (LOC), post-traumatic amnesia (PTA) or confusion/disorientation) and neurological symptoms. RESULTS: Among veterans who screened positive on the initial VA TBI and then received a clinician evaluation, 60% were confirmed to have a TBI diagnosis. Veterans reporting at least one LOC, confusion or PTA were almost 18-times more likely to receive a confirmed TBI diagnosis. Odds of clinician-confirmed TBI were 2.5-3-times greater among those who endorsed dizziness, poor coordination, headaches, nausea, vision problems and/or irritability, compared to those not endorsing these symptoms. Nausea had greatest utility for confirming a TBI. CONCLUSIONS: Identification of neurologic symptoms that most contribute to a clinician-confirmed diagnosis of TBI has potential for streamlining detection of TBI and symptoms needed for treatment.},
keywords = {*Afghan Campaign 2001-, *Brain Concussion/di [Diagnosis], *Iraq War, *Veterans/sn [Statistics \& Numerical Data], 2003-2011, adult, Brain Concussion/pp [Physiopathology], Brain Concussion/px [Psychology], Cohort Studies, Female, Humans, Injury Severity Score, Male, middle aged, Military personnel, Post-Traumatic/di [Diagnosis], Post-Traumatic/pp [Physiopatholo, Post-Traumatic/px [Psychology], Retrospective Studies, self report, Stress Disorders, UNITED States, United States Department of Veterans Affairs},
pubstate = {published},
tppubtype = {article}
}
Williams, R M; Dowling, M; O'Connor, K L
Head Impact Measurement Devices Journal Article
In: Sports & Health, vol. 8, no. 3, pp. 270–273, 2016.
Abstract | BibTeX | Tags: *Accelerometry, *Athletic Injuries/di [Diagnosis], *Brain Concussion/di [Diagnosis], Athletic Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Head Protective Devices, Head/pp [Physiopathology], Humans
@article{Williams2016b,
title = {Head Impact Measurement Devices},
author = {Williams, R M and Dowling, M and O'Connor, K L},
year = {2016},
date = {2016-01-01},
journal = {Sports \& Health},
volume = {8},
number = {3},
pages = {270--273},
abstract = {CONTEXT: Concussive injuries are at the forefront of sports medicine research. Recently, researchers have used a variety of head- and helmet-based impact-monitoring devices to quantify impacts sustained during contact sport participation. This review provides an up-to-date collection of head accelerometer use at the youth, high school, and collegiate levels. EVIDENCE ACQUISITION: PubMed was searched for articles published between 1980 and 2015 using the terms accelerometer and concussion, impact sensor and concussion, head impact telemetry system, head impact telemetry, and linear acceleration and concussion. An additional Google search was performed to capture devices without publications. STUDY DESIGN: Clinical review. LEVEL OF EVIDENCE: Level 4. RESULTS: Twenty-four products track and/or record head impact for clinical or research use. Ten of these head impact devices have publications supporting their utility. CONCLUSION: Head impact measuring devices can describe athlete exposure in terms of magnitude and/or frequency, highlighting their utility within a multimodal approach for concussion assessment and diagnosis.},
keywords = {*Accelerometry, *Athletic Injuries/di [Diagnosis], *Brain Concussion/di [Diagnosis], Athletic Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Head Protective Devices, Head/pp [Physiopathology], Humans},
pubstate = {published},
tppubtype = {article}
}
Little, C E; Emery, C; Black, A; Scott, S H; Meeuwisse, W; Nettel-Aguirre, A; Benson, B; Dukelow, S
Test-retest reliability of KINARM robot sensorimotor and cognitive assessment: in pediatric ice hockey players Journal Article
In: Journal of Neuroengineering & Rehabilitation, vol. 12, pp. 78, 2015.
Abstract | BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/px [Psychology], *COGNITION, *Hockey/in [Injuries], *Robotics, *Sensation, Adolescent, Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Child, Computer simulation, Humans, learning, Longitudinal studies, Male, Neuropsychological Tests, Practice (Psychology), Prognosis, Prospective Studies, Psychomotor Performance/ph [Physiology], Reproducibility of Results, treatment outcome
@article{Little2015,
title = {Test-retest reliability of KINARM robot sensorimotor and cognitive assessment: in pediatric ice hockey players},
author = {Little, C E and Emery, C and Black, A and Scott, S H and Meeuwisse, W and Nettel-Aguirre, A and Benson, B and Dukelow, S},
year = {2015},
date = {2015-01-01},
journal = {Journal of Neuroengineering \& Rehabilitation},
volume = {12},
pages = {78},
abstract = {BACKGROUND: Better diagnostic and prognostic tools are needed to address issues related to early diagnosis and management of concussion across the continuum of aging but particularly in children and adolescents. The purpose of the current study was to evaluate the reliability of robotic technology (KINARM robot) assessments of reaching, position sense, bimanual motor function, visuospatial skills, attention and decision making in youth ice hockey players (ages 10-14). METHODS: Thirty-four male children attended two testing days, one week apart. On day one, each subject completed five tasks on the robot with two examiners (alternating examiner sequence); the 2(nd) examiner followed the same procedure as the 1(st) immediately afterwards. One consistent examiner tested subjects one week later. This is a test-retest reliability study. The robotic tasks characterize sensorimotor and/or cognitive performance; 63 parameters from 5 tasks are reported. Session 1 was the 1(st) time the subject performed the 5 tasks, session 2 the 2(nd) time on day 1, and session 3 one week following. RESULTS: Intra-class correlation coefficients ranged from 0.06 to 0.91 and 0.09 to 0.90 for session 1 to 2 and 2 to 3, respectively. Bland-Altman plots showed agreement in a majority of the parameters and a learning effect in 25 % and 24 % of parameters in session 1 vs 2 and 1 vs 3, respectively but none for session 2 vs 3. Of those that showed a learning effect, only 8 % of parameters in session 1 vs 2 and 10 % in session 1 vs 3 had a clinical relevance measure\>0.8. CONCLUSIONS: The relative homogeneity of the sample and the effect of learning seen in some of the task parameters appears to have negatively impacted the intra-class correlation coefficients from session 1 to 2, with less impact for 2 to 3. The Bland-Altman analysis supports good absolute reliability in healthy male children with no neurological impairment ranging in age from 10 to 14. The clinically relevant learning effect seen, in a small number of parameters could be addressed by creating a learning effect adjustment factor and/or implementing a practice session, which would eliminate the learning effect.},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/px [Psychology], *COGNITION, *Hockey/in [Injuries], *Robotics, *Sensation, Adolescent, Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Child, Computer simulation, Humans, learning, Longitudinal studies, Male, Neuropsychological Tests, Practice (Psychology), Prognosis, Prospective Studies, Psychomotor Performance/ph [Physiology], Reproducibility of Results, treatment outcome},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {*Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]},
pubstate = {published},
tppubtype = {article}
}
Utecht, B
Concussed Journal Article
In: Neurology, vol. 83, no. 13, pp. 1126–1127, 2014.
BibTeX | Tags: *Athletic Injuries, *Brain Concussion, *Memory/ph [Physiology], Athletic Injuries/et [Etiology], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Humans, Sports
@article{Utecht2014,
title = {Concussed},
author = {Utecht, B},
year = {2014},
date = {2014-01-01},
journal = {Neurology},
volume = {83},
number = {13},
pages = {1126--1127},
keywords = {*Athletic Injuries, *Brain Concussion, *Memory/ph [Physiology], Athletic Injuries/et [Etiology], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Humans, Sports},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]},
pubstate = {published},
tppubtype = {article}
}
Horner, A; VanDemark, M; Jensen, G A
The challenge of assessing a patient with dementia and head injury Journal Article
In: AACN Clinical Issues, vol. 13, no. 1, pp. 73–83, 2002.
Abstract | BibTeX | Tags: *Craniocerebral Trauma/co [Complications], *Dementia/co [Complications], Accidental Falls, Accidents, aged, Alzheimer Disease/di [Diagnosis], Brain Concussion/di [Diagnosis], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Craniocerebral Trauma/di [Diagnosis], Craniocerebral Trauma/pp [Physiopathology], Delirium/di [Diagnosis], Delirium/et [Etiology], Home, Humans
@article{Horner2002,
title = {The challenge of assessing a patient with dementia and head injury},
author = {Horner, A and VanDemark, M and Jensen, G A},
year = {2002},
date = {2002-01-01},
journal = {AACN Clinical Issues},
volume = {13},
number = {1},
pages = {73--83},
abstract = {Alzheimer's disease is emerging as a major health challenge for the 21st century. The reported case study discusses a 74-year-old woman with dementia of the Alzheimer type who sustained a head injury when she fell down the basement stairs. Differentiating the head injury from the preexisting dementia was complicated and required creative and astute assessment. Objective assessment tools discussed include the Mini-Mental State Examination, a delirium guide, and the Tinetti assessment tool. Predisposition to delirium is significant because of the comorbidities associated with cognitive impairment and head injury. Interventions to prevent delirium are recommended.},
keywords = {*Craniocerebral Trauma/co [Complications], *Dementia/co [Complications], Accidental Falls, Accidents, aged, Alzheimer Disease/di [Diagnosis], Brain Concussion/di [Diagnosis], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Craniocerebral Trauma/di [Diagnosis], Craniocerebral Trauma/pp [Physiopathology], Delirium/di [Diagnosis], Delirium/et [Etiology], Home, Humans},
pubstate = {published},
tppubtype = {article}
}
Lau, K M; Madden, E; Neylan, T C; Seal, K H; Maguen, S
Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors Journal Article
In: Brain Injury, vol. 30, no. 3, pp. 287–294, 2016.
@article{Lau2016a,
title = {Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors},
author = {Lau, K M and Madden, E and Neylan, T C and Seal, K H and Maguen, S},
year = {2016},
date = {2016-01-01},
journal = {Brain Injury},
volume = {30},
number = {3},
pages = {287--294},
abstract = {OBJECTIVE: To investigate injury severity markers and neurological symptoms associated with clinician-confirmed mild traumatic brain injury (TBI) among Iraq and Afghanistan veterans. SETTING: Department of Veterans Affairs (VA) medical centre and five affiliated community-based outpatient clinics. PARTICIPANTS: Three hundred and fifty Iraq and Afghanistan veterans with positive initial VA TBI screens between 1 April 2007 and 1 June 2010 and clinician-confirmed TBI status by 1 December 2010. METHODS: Retrospective-cohort study of medical record data. Main measures included clinician-confirmed TBI status, injury severity markers (e.g. loss of consciousness (LOC), post-traumatic amnesia (PTA) or confusion/disorientation) and neurological symptoms. RESULTS: Among veterans who screened positive on the initial VA TBI and then received a clinician evaluation, 60% were confirmed to have a TBI diagnosis. Veterans reporting at least one LOC, confusion or PTA were almost 18-times more likely to receive a confirmed TBI diagnosis. Odds of clinician-confirmed TBI were 2.5-3-times greater among those who endorsed dizziness, poor coordination, headaches, nausea, vision problems and/or irritability, compared to those not endorsing these symptoms. Nausea had greatest utility for confirming a TBI. CONCLUSIONS: Identification of neurologic symptoms that most contribute to a clinician-confirmed diagnosis of TBI has potential for streamlining detection of TBI and symptoms needed for treatment.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Williams, R M; Dowling, M; O'Connor, K L
Head Impact Measurement Devices Journal Article
In: Sports & Health, vol. 8, no. 3, pp. 270–273, 2016.
@article{Williams2016b,
title = {Head Impact Measurement Devices},
author = {Williams, R M and Dowling, M and O'Connor, K L},
year = {2016},
date = {2016-01-01},
journal = {Sports \& Health},
volume = {8},
number = {3},
pages = {270--273},
abstract = {CONTEXT: Concussive injuries are at the forefront of sports medicine research. Recently, researchers have used a variety of head- and helmet-based impact-monitoring devices to quantify impacts sustained during contact sport participation. This review provides an up-to-date collection of head accelerometer use at the youth, high school, and collegiate levels. EVIDENCE ACQUISITION: PubMed was searched for articles published between 1980 and 2015 using the terms accelerometer and concussion, impact sensor and concussion, head impact telemetry system, head impact telemetry, and linear acceleration and concussion. An additional Google search was performed to capture devices without publications. STUDY DESIGN: Clinical review. LEVEL OF EVIDENCE: Level 4. RESULTS: Twenty-four products track and/or record head impact for clinical or research use. Ten of these head impact devices have publications supporting their utility. CONCLUSION: Head impact measuring devices can describe athlete exposure in terms of magnitude and/or frequency, highlighting their utility within a multimodal approach for concussion assessment and diagnosis.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Little, C E; Emery, C; Black, A; Scott, S H; Meeuwisse, W; Nettel-Aguirre, A; Benson, B; Dukelow, S
Test-retest reliability of KINARM robot sensorimotor and cognitive assessment: in pediatric ice hockey players Journal Article
In: Journal of Neuroengineering & Rehabilitation, vol. 12, pp. 78, 2015.
@article{Little2015,
title = {Test-retest reliability of KINARM robot sensorimotor and cognitive assessment: in pediatric ice hockey players},
author = {Little, C E and Emery, C and Black, A and Scott, S H and Meeuwisse, W and Nettel-Aguirre, A and Benson, B and Dukelow, S},
year = {2015},
date = {2015-01-01},
journal = {Journal of Neuroengineering \& Rehabilitation},
volume = {12},
pages = {78},
abstract = {BACKGROUND: Better diagnostic and prognostic tools are needed to address issues related to early diagnosis and management of concussion across the continuum of aging but particularly in children and adolescents. The purpose of the current study was to evaluate the reliability of robotic technology (KINARM robot) assessments of reaching, position sense, bimanual motor function, visuospatial skills, attention and decision making in youth ice hockey players (ages 10-14). METHODS: Thirty-four male children attended two testing days, one week apart. On day one, each subject completed five tasks on the robot with two examiners (alternating examiner sequence); the 2(nd) examiner followed the same procedure as the 1(st) immediately afterwards. One consistent examiner tested subjects one week later. This is a test-retest reliability study. The robotic tasks characterize sensorimotor and/or cognitive performance; 63 parameters from 5 tasks are reported. Session 1 was the 1(st) time the subject performed the 5 tasks, session 2 the 2(nd) time on day 1, and session 3 one week following. RESULTS: Intra-class correlation coefficients ranged from 0.06 to 0.91 and 0.09 to 0.90 for session 1 to 2 and 2 to 3, respectively. Bland-Altman plots showed agreement in a majority of the parameters and a learning effect in 25 % and 24 % of parameters in session 1 vs 2 and 1 vs 3, respectively but none for session 2 vs 3. Of those that showed a learning effect, only 8 % of parameters in session 1 vs 2 and 10 % in session 1 vs 3 had a clinical relevance measure\>0.8. CONCLUSIONS: The relative homogeneity of the sample and the effect of learning seen in some of the task parameters appears to have negatively impacted the intra-class correlation coefficients from session 1 to 2, with less impact for 2 to 3. The Bland-Altman analysis supports good absolute reliability in healthy male children with no neurological impairment ranging in age from 10 to 14. The clinically relevant learning effect seen, in a small number of parameters could be addressed by creating a learning effect adjustment factor and/or implementing a practice session, which would eliminate the learning effect.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Utecht, B
Concussed Journal Article
In: Neurology, vol. 83, no. 13, pp. 1126–1127, 2014.
@article{Utecht2014,
title = {Concussed},
author = {Utecht, B},
year = {2014},
date = {2014-01-01},
journal = {Neurology},
volume = {83},
number = {13},
pages = {1126--1127},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Horner, A; VanDemark, M; Jensen, G A
The challenge of assessing a patient with dementia and head injury Journal Article
In: AACN Clinical Issues, vol. 13, no. 1, pp. 73–83, 2002.
@article{Horner2002,
title = {The challenge of assessing a patient with dementia and head injury},
author = {Horner, A and VanDemark, M and Jensen, G A},
year = {2002},
date = {2002-01-01},
journal = {AACN Clinical Issues},
volume = {13},
number = {1},
pages = {73--83},
abstract = {Alzheimer's disease is emerging as a major health challenge for the 21st century. The reported case study discusses a 74-year-old woman with dementia of the Alzheimer type who sustained a head injury when she fell down the basement stairs. Differentiating the head injury from the preexisting dementia was complicated and required creative and astute assessment. Objective assessment tools discussed include the Mini-Mental State Examination, a delirium guide, and the Tinetti assessment tool. Predisposition to delirium is significant because of the comorbidities associated with cognitive impairment and head injury. Interventions to prevent delirium are recommended.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lau, K M; Madden, E; Neylan, T C; Seal, K H; Maguen, S
Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors Journal Article
In: Brain Injury, vol. 30, no. 3, pp. 287–294, 2016.
Abstract | BibTeX | Tags: *Afghan Campaign 2001-, *Brain Concussion/di [Diagnosis], *Iraq War, *Veterans/sn [Statistics & Numerical Data], 2003-2011, adult, Brain Concussion/pp [Physiopathology], Brain Concussion/px [Psychology], Cohort Studies, Female, Humans, Injury Severity Score, Male, middle aged, Military personnel, Post-Traumatic/di [Diagnosis], Post-Traumatic/pp [Physiopatholo, Post-Traumatic/px [Psychology], Retrospective Studies, self report, Stress Disorders, UNITED States, United States Department of Veterans Affairs
@article{Lau2016a,
title = {Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors},
author = {Lau, K M and Madden, E and Neylan, T C and Seal, K H and Maguen, S},
year = {2016},
date = {2016-01-01},
journal = {Brain Injury},
volume = {30},
number = {3},
pages = {287--294},
abstract = {OBJECTIVE: To investigate injury severity markers and neurological symptoms associated with clinician-confirmed mild traumatic brain injury (TBI) among Iraq and Afghanistan veterans. SETTING: Department of Veterans Affairs (VA) medical centre and five affiliated community-based outpatient clinics. PARTICIPANTS: Three hundred and fifty Iraq and Afghanistan veterans with positive initial VA TBI screens between 1 April 2007 and 1 June 2010 and clinician-confirmed TBI status by 1 December 2010. METHODS: Retrospective-cohort study of medical record data. Main measures included clinician-confirmed TBI status, injury severity markers (e.g. loss of consciousness (LOC), post-traumatic amnesia (PTA) or confusion/disorientation) and neurological symptoms. RESULTS: Among veterans who screened positive on the initial VA TBI and then received a clinician evaluation, 60% were confirmed to have a TBI diagnosis. Veterans reporting at least one LOC, confusion or PTA were almost 18-times more likely to receive a confirmed TBI diagnosis. Odds of clinician-confirmed TBI were 2.5-3-times greater among those who endorsed dizziness, poor coordination, headaches, nausea, vision problems and/or irritability, compared to those not endorsing these symptoms. Nausea had greatest utility for confirming a TBI. CONCLUSIONS: Identification of neurologic symptoms that most contribute to a clinician-confirmed diagnosis of TBI has potential for streamlining detection of TBI and symptoms needed for treatment.},
keywords = {*Afghan Campaign 2001-, *Brain Concussion/di [Diagnosis], *Iraq War, *Veterans/sn [Statistics \& Numerical Data], 2003-2011, adult, Brain Concussion/pp [Physiopathology], Brain Concussion/px [Psychology], Cohort Studies, Female, Humans, Injury Severity Score, Male, middle aged, Military personnel, Post-Traumatic/di [Diagnosis], Post-Traumatic/pp [Physiopatholo, Post-Traumatic/px [Psychology], Retrospective Studies, self report, Stress Disorders, UNITED States, United States Department of Veterans Affairs},
pubstate = {published},
tppubtype = {article}
}
Williams, R M; Dowling, M; O'Connor, K L
Head Impact Measurement Devices Journal Article
In: Sports & Health, vol. 8, no. 3, pp. 270–273, 2016.
Abstract | BibTeX | Tags: *Accelerometry, *Athletic Injuries/di [Diagnosis], *Brain Concussion/di [Diagnosis], Athletic Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Head Protective Devices, Head/pp [Physiopathology], Humans
@article{Williams2016b,
title = {Head Impact Measurement Devices},
author = {Williams, R M and Dowling, M and O'Connor, K L},
year = {2016},
date = {2016-01-01},
journal = {Sports \& Health},
volume = {8},
number = {3},
pages = {270--273},
abstract = {CONTEXT: Concussive injuries are at the forefront of sports medicine research. Recently, researchers have used a variety of head- and helmet-based impact-monitoring devices to quantify impacts sustained during contact sport participation. This review provides an up-to-date collection of head accelerometer use at the youth, high school, and collegiate levels. EVIDENCE ACQUISITION: PubMed was searched for articles published between 1980 and 2015 using the terms accelerometer and concussion, impact sensor and concussion, head impact telemetry system, head impact telemetry, and linear acceleration and concussion. An additional Google search was performed to capture devices without publications. STUDY DESIGN: Clinical review. LEVEL OF EVIDENCE: Level 4. RESULTS: Twenty-four products track and/or record head impact for clinical or research use. Ten of these head impact devices have publications supporting their utility. CONCLUSION: Head impact measuring devices can describe athlete exposure in terms of magnitude and/or frequency, highlighting their utility within a multimodal approach for concussion assessment and diagnosis.},
keywords = {*Accelerometry, *Athletic Injuries/di [Diagnosis], *Brain Concussion/di [Diagnosis], Athletic Injuries/pp [Physiopathology], Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Head Protective Devices, Head/pp [Physiopathology], Humans},
pubstate = {published},
tppubtype = {article}
}
Little, C E; Emery, C; Black, A; Scott, S H; Meeuwisse, W; Nettel-Aguirre, A; Benson, B; Dukelow, S
Test-retest reliability of KINARM robot sensorimotor and cognitive assessment: in pediatric ice hockey players Journal Article
In: Journal of Neuroengineering & Rehabilitation, vol. 12, pp. 78, 2015.
Abstract | BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/px [Psychology], *COGNITION, *Hockey/in [Injuries], *Robotics, *Sensation, Adolescent, Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Child, Computer simulation, Humans, learning, Longitudinal studies, Male, Neuropsychological Tests, Practice (Psychology), Prognosis, Prospective Studies, Psychomotor Performance/ph [Physiology], Reproducibility of Results, treatment outcome
@article{Little2015,
title = {Test-retest reliability of KINARM robot sensorimotor and cognitive assessment: in pediatric ice hockey players},
author = {Little, C E and Emery, C and Black, A and Scott, S H and Meeuwisse, W and Nettel-Aguirre, A and Benson, B and Dukelow, S},
year = {2015},
date = {2015-01-01},
journal = {Journal of Neuroengineering \& Rehabilitation},
volume = {12},
pages = {78},
abstract = {BACKGROUND: Better diagnostic and prognostic tools are needed to address issues related to early diagnosis and management of concussion across the continuum of aging but particularly in children and adolescents. The purpose of the current study was to evaluate the reliability of robotic technology (KINARM robot) assessments of reaching, position sense, bimanual motor function, visuospatial skills, attention and decision making in youth ice hockey players (ages 10-14). METHODS: Thirty-four male children attended two testing days, one week apart. On day one, each subject completed five tasks on the robot with two examiners (alternating examiner sequence); the 2(nd) examiner followed the same procedure as the 1(st) immediately afterwards. One consistent examiner tested subjects one week later. This is a test-retest reliability study. The robotic tasks characterize sensorimotor and/or cognitive performance; 63 parameters from 5 tasks are reported. Session 1 was the 1(st) time the subject performed the 5 tasks, session 2 the 2(nd) time on day 1, and session 3 one week following. RESULTS: Intra-class correlation coefficients ranged from 0.06 to 0.91 and 0.09 to 0.90 for session 1 to 2 and 2 to 3, respectively. Bland-Altman plots showed agreement in a majority of the parameters and a learning effect in 25 % and 24 % of parameters in session 1 vs 2 and 1 vs 3, respectively but none for session 2 vs 3. Of those that showed a learning effect, only 8 % of parameters in session 1 vs 2 and 10 % in session 1 vs 3 had a clinical relevance measure\>0.8. CONCLUSIONS: The relative homogeneity of the sample and the effect of learning seen in some of the task parameters appears to have negatively impacted the intra-class correlation coefficients from session 1 to 2, with less impact for 2 to 3. The Bland-Altman analysis supports good absolute reliability in healthy male children with no neurological impairment ranging in age from 10 to 14. The clinically relevant learning effect seen, in a small number of parameters could be addressed by creating a learning effect adjustment factor and/or implementing a practice session, which would eliminate the learning effect.},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/px [Psychology], *COGNITION, *Hockey/in [Injuries], *Robotics, *Sensation, Adolescent, Biomechanical Phenomena, Brain Concussion/pp [Physiopathology], Child, Computer simulation, Humans, learning, Longitudinal studies, Male, Neuropsychological Tests, Practice (Psychology), Prognosis, Prospective Studies, Psychomotor Performance/ph [Physiology], Reproducibility of Results, treatment outcome},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {*Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]},
pubstate = {published},
tppubtype = {article}
}
Utecht, B
Concussed Journal Article
In: Neurology, vol. 83, no. 13, pp. 1126–1127, 2014.
BibTeX | Tags: *Athletic Injuries, *Brain Concussion, *Memory/ph [Physiology], Athletic Injuries/et [Etiology], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Humans, Sports
@article{Utecht2014,
title = {Concussed},
author = {Utecht, B},
year = {2014},
date = {2014-01-01},
journal = {Neurology},
volume = {83},
number = {13},
pages = {1126--1127},
keywords = {*Athletic Injuries, *Brain Concussion, *Memory/ph [Physiology], Athletic Injuries/et [Etiology], Athletic Injuries/pp [Physiopathology], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Humans, Sports},
pubstate = {published},
tppubtype = {article}
}
Dubourg, J; Messerer, M
Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction Journal Article
In: Neurosurgical Focus, vol. 31, no. 5, pp. E2, 2011.
Abstract | BibTeX | Tags: *Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]
@article{Dubourg2011,
title = {Sports-related chronic repetitive head trauma as a cause of pituitary dysfunction},
author = {Dubourg, J and Messerer, M},
year = {2011},
date = {2011-01-01},
journal = {Neurosurgical Focus},
volume = {31},
number = {5},
pages = {E2},
abstract = {Traumatic brain injury (TBI) is recognized as a cause of hypopituitarism even after mild TBI. Although over the past decade, a growing body of research has detailed neuroendocrine changes induced by TBI, the mechanisms and risk factors responsible for this pituitary dysfunction are still unclear. Around the world, sports-especially combative sports-are very popular. However, sports are not generally considered as a cause of TBI in most epidemiological studies, and the link between sports-related head trauma and hypopituitarism has not been investigated until recently. Thus, there is a paucity of data regarding this important concern. Because of the large number of young sports participants with near-normal life expectancy, the implications of undiagnosed or untreated postconcussion pituitary dysfunction can be dramatic. Understanding the pathophysiological mechanisms and risk factors of hypopituitarism caused by sports injuries is thus an important issue that concerns both medical staff and sponsors of sports. The aim of this paper was to summarize the best evidence for understanding the pathophysiological mechanisms and to discuss the current data and recommendations on sports-related head trauma as a cause of hypopituitarism.},
keywords = {*Athletic Injuries/pp [Physiopathology], *Brain Injuries/pp [Physiopathology], *HEAD injuries, *Pituitary Diseases/et [Etiology], *Pituitary Gland/pp [Physiopathology], Athletic Injuries/co [Complications], Brain Concussion/co [Complications], Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain Injuries/et [Etiology], chronic disease, Closed/co [Complications], Closed/pp [Physiopathology], Early Diagnosis, Head Injuries, Humans, Pituitary Diseases/pp [Physiopathology], Pituitary Gland/in [Injuries]},
pubstate = {published},
tppubtype = {article}
}
Horner, A; VanDemark, M; Jensen, G A
The challenge of assessing a patient with dementia and head injury Journal Article
In: AACN Clinical Issues, vol. 13, no. 1, pp. 73–83, 2002.
Abstract | BibTeX | Tags: *Craniocerebral Trauma/co [Complications], *Dementia/co [Complications], Accidental Falls, Accidents, aged, Alzheimer Disease/di [Diagnosis], Brain Concussion/di [Diagnosis], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Craniocerebral Trauma/di [Diagnosis], Craniocerebral Trauma/pp [Physiopathology], Delirium/di [Diagnosis], Delirium/et [Etiology], Home, Humans
@article{Horner2002,
title = {The challenge of assessing a patient with dementia and head injury},
author = {Horner, A and VanDemark, M and Jensen, G A},
year = {2002},
date = {2002-01-01},
journal = {AACN Clinical Issues},
volume = {13},
number = {1},
pages = {73--83},
abstract = {Alzheimer's disease is emerging as a major health challenge for the 21st century. The reported case study discusses a 74-year-old woman with dementia of the Alzheimer type who sustained a head injury when she fell down the basement stairs. Differentiating the head injury from the preexisting dementia was complicated and required creative and astute assessment. Objective assessment tools discussed include the Mini-Mental State Examination, a delirium guide, and the Tinetti assessment tool. Predisposition to delirium is significant because of the comorbidities associated with cognitive impairment and head injury. Interventions to prevent delirium are recommended.},
keywords = {*Craniocerebral Trauma/co [Complications], *Dementia/co [Complications], Accidental Falls, Accidents, aged, Alzheimer Disease/di [Diagnosis], Brain Concussion/di [Diagnosis], Brain Concussion/et [Etiology], Brain Concussion/pp [Physiopathology], Craniocerebral Trauma/di [Diagnosis], Craniocerebral Trauma/pp [Physiopathology], Delirium/di [Diagnosis], Delirium/et [Etiology], Home, Humans},
pubstate = {published},
tppubtype = {article}
}