Stewart, W; McNamara, P H; Lawlor, B; Hutchinson, S; Farrell, M
Chronic traumatic encephalopathy: a potential late and under recognized consequence of rugby union? Journal Article
In: Qjm, vol. 109, no. 1, pp. 11–15, 2016.
Abstract | BibTeX | Tags: *Brain Concussion/co [Complications], *Brain Injury, *Brain/pp [Physiopathology], *Football/in [Injuries], *Neurodegenerative Diseases/pp [Physiopathology], Chronic/pa [Pathology], Humans, Magnetic Resonance Imaging, Male, middle aged, neurologic examination
@article{Stewart2016,
title = {Chronic traumatic encephalopathy: a potential late and under recognized consequence of rugby union?},
author = {Stewart, W and McNamara, P H and Lawlor, B and Hutchinson, S and Farrell, M},
year = {2016},
date = {2016-01-01},
journal = {Qjm},
volume = {109},
number = {1},
pages = {11--15},
abstract = {The association between exposure to head injury and increased risk of neurodegenerative disease, specifically chronic traumatic encephalopathy (CTE), is widely recognized. Historically, this was largely considered a phenomenon restricted to boxers, with more recent case series identifying further 'high risk' individuals, such as former American footballers, or military personnel. However, in all cases thus far reported, it is clear that it is the exposure to head injury which is associated with increased dementia risk, and not the circumstances or environment of exposure. As such, there is considerable potential for under-recognition of CTE in patients presenting with neurodegenerative disease, particularly where head injury exposure might have been historical and through sport. This article reviews current understanding of CTE and, via an illustrative case in rugby union, highlights the value of a detailed history on head injury and also draws attention to imaging studies in assessing patients with neurodegenerative disease. Copyright © The Author 2015. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.},
keywords = {*Brain Concussion/co [Complications], *Brain Injury, *Brain/pp [Physiopathology], *Football/in [Injuries], *Neurodegenerative Diseases/pp [Physiopathology], Chronic/pa [Pathology], Humans, Magnetic Resonance Imaging, Male, middle aged, neurologic examination},
pubstate = {published},
tppubtype = {article}
}
Auerbach, P S; Waggoner 2nd, W H
It's Time to Change the Rules Journal Article
In: JAMA, vol. 316, no. 12, pp. 1260–1261, 2016.
BibTeX | Tags: *Brain Concussion/co [Complications], *Football/in [Injuries], adult, Brain Concussion/et [Etiology], Brain Concussion/pc [Prevention & Control], Football/st [Standards], Humans, Male, Safety/st [Standards], UNITED States
@article{Auerbach2016,
title = {It's Time to Change the Rules},
author = {Auerbach, P S and {Waggoner 2nd}, W H},
year = {2016},
date = {2016-01-01},
journal = {JAMA},
volume = {316},
number = {12},
pages = {1260--1261},
keywords = {*Brain Concussion/co [Complications], *Football/in [Injuries], adult, Brain Concussion/et [Etiology], Brain Concussion/pc [Prevention \& Control], Football/st [Standards], Humans, Male, Safety/st [Standards], UNITED States},
pubstate = {published},
tppubtype = {article}
}
McCarthy, M
Undercounting of football concussions skewed NFL research, US investigation alleges Journal Article
In: BMJ, vol. 352, pp. i1788, 2016.
BibTeX | Tags: *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Biomedical Research/sn [Statistics & Numerical Dat, Football/sn [Statistics & Numerical Data], Humans, Research Design/sn [Statistics & Numerical Data], United States/ep [Epidemiology]
@article{McCarthy2016b,
title = {Undercounting of football concussions skewed NFL research, US investigation alleges},
author = {McCarthy, M},
year = {2016},
date = {2016-01-01},
journal = {BMJ},
volume = {352},
pages = {i1788},
keywords = {*Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Biomedical Research/sn [Statistics \& Numerical Dat, Football/sn [Statistics \& Numerical Data], Humans, Research Design/sn [Statistics \& Numerical Data], United States/ep [Epidemiology]},
pubstate = {published},
tppubtype = {article}
}
Lucke-Wold, B P; Turner, R C; Logsdon, A F; Nguyen, L; Bailes, J E; Lee, J M; Robson, M J; Omalu, B I; Huber, J D; Rosen, C L
Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy Journal Article
In: Journal of Neurosurgery, vol. 124, no. 3, pp. 687–702, 2016.
Abstract | BibTeX | Tags: *Blast Injuries/px [Psychology], *Brain Injury, *Endoplasmic Reticulum Stress/ph [Physiology], *Football/in [Injuries], *Wrestling/in [Injuries], adult, animal, Animals, Blast Injuries/et [Etiology], Blast Injuries/pa [Pathology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Disease Models, Humans, Male, Rats, Sprague-Dawley
@article{Lucke-Wold2016,
title = {Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy},
author = {Lucke-Wold, B P and Turner, R C and Logsdon, A F and Nguyen, L and Bailes, J E and Lee, J M and Robson, M J and Omalu, B I and Huber, J D and Rosen, C L},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neurosurgery},
volume = {124},
number = {3},
pages = {687--702},
abstract = {OBJECTIVE: Chronic traumatic encephalopathy is a progressive neurodegenerative disease characterized by neurofibrillary tau tangles following repetitive neurotrauma. The underlying mechanism linking traumatic brain injury to chronic traumatic encephalopathy has not been elucidated. The authors investigate the role of endoplasmic reticulum stress as a link between acute neurotrauma and chronic neurodegeneration. METHODS: The authors used pharmacological, biochemical, and behavioral tools to assess the role of endoplasmic reticulum stress in linking acute repetitive traumatic brain injury to the development of chronic neurodegeneration. Data from the authors' clinically relevant and validated rodent blast model were compared with those obtained from postmortem human chronic traumatic encephalopathy specimens from a National Football League player and World Wrestling Entertainment wrestler. RESULTS: The results demonstrated strong correlation of endoplasmic reticulum stress activation with subsequent tau hyperphosphorylation. Various endoplasmic reticulum stress markers were increased in human chronic traumatic encephalopathy specimens, and the endoplasmic reticulum stress response was associated with an increase in the tau kinase, glycogen synthase kinase-3beta. Docosahexaenoic acid, an endoplasmic reticulum stress inhibitor, improved cognitive performance in the rat model 3 weeks after repetitive blast exposure. The data showed that docosahexaenoic acid administration substantially reduced tau hyperphosphorylation (t = 4.111, p \< 0.05), improved cognition (t = 6.532, p \< 0.001), and inhibited C/EBP homology protein activation (t = 5.631, p \< 0.01). Additionally the data showed, for the first time, that endoplasmic reticulum stress is involved in the pathophysiology of chronic traumatic encephalopathy. CONCLUSIONS: Docosahexaenoic acid therefore warrants further investigation as a potential therapeutic agent for the prevention of chronic traumatic encephalopathy.},
keywords = {*Blast Injuries/px [Psychology], *Brain Injury, *Endoplasmic Reticulum Stress/ph [Physiology], *Football/in [Injuries], *Wrestling/in [Injuries], adult, animal, Animals, Blast Injuries/et [Etiology], Blast Injuries/pa [Pathology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Disease Models, Humans, Male, Rats, Sprague-Dawley},
pubstate = {published},
tppubtype = {article}
}
Iverson, G L
Suicide and Chronic Traumatic Encephalopathy Journal Article
In: Journal of Neuropsychiatry & Clinical Neurosciences, vol. 28, no. 1, pp. 9–16, 2016.
Abstract | BibTeX | Tags: *Brain Injury, *Football/in [Injuries], *Suicide/px [Psychology], Athletic Injuries/di [Diagnosis], Athletic Injuries/ep [Epidemiology], Athletic Injuries/px [Psychology], Brain Injury, Chronic/di [Diagnosis], Chronic/ep [Epidemiology], Chronic/px [Psychology], Football/px [Psychology], Humans, Male, Risk Factors, Suicide/td [Trends]
@article{Iverson2016a,
title = {Suicide and Chronic Traumatic Encephalopathy},
author = {Iverson, G L},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neuropsychiatry \& Clinical Neurosciences},
volume = {28},
number = {1},
pages = {9--16},
abstract = {For nearly 80 years, suicidality was not considered to be a core clinical feature of chronic traumatic encephalopathy (CTE). In recent years, suicide has been widely cited as being associated with CTE, and now depression has been proposed to be one of three core diagnostic features alongside cognitive impairment and anger control problems. This evolution of the clinical features has been reinforced by thousands of media stories reporting a connection between mental health problems in former athletes and military veterans, repetitive neurotrauma, and CTE. At present, the science underlying the causal assumption between repetitive neurotrauma, depression, suicide, and the neuropathology believed to be unique to CTE is inconclusive. Epidemiological evidence indicates that former National Football League players, for example, are at lower, not greater, risk for suicide than men in the general population. This article aims to discuss the critical issues and literature relating to these possible relationships.},
keywords = {*Brain Injury, *Football/in [Injuries], *Suicide/px [Psychology], Athletic Injuries/di [Diagnosis], Athletic Injuries/ep [Epidemiology], Athletic Injuries/px [Psychology], Brain Injury, Chronic/di [Diagnosis], Chronic/ep [Epidemiology], Chronic/px [Psychology], Football/px [Psychology], Humans, Male, Risk Factors, Suicide/td [Trends]},
pubstate = {published},
tppubtype = {article}
}
Samadani, U
Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 21, pp. 2097–2098, 2016.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans
@article{Samadani2016,
title = {Physicians and Youth Tackle Football},
author = {Samadani, U},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {21},
pages = {2097--2098},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans},
pubstate = {published},
tppubtype = {article}
}
Koerte, I K; Hufschmidt, J; Muehlmann, M; Tripodis, Y; Stamm, J M; Pasternak, O; Giwerc, M Y; Coleman, M J; Baugh, C M; Fritts, N G; Heinen, F; Lin, A; Stern, R A; Shenton, M E
Cavum Septi Pellucidi in Symptomatic Former Professional Football Players Journal Article
In: Journal of Neurotrauma, vol. 33, no. 4, pp. 346–353, 2016.
Abstract | BibTeX | Tags: *Athletes, *Football/in [Injuries], *Septum Pellucidum/pa [Pathology], adult, aged, Brain Concussion/di [Diagnosis], Brain Concussion/ep [Epidemiology], Humans, Male, middle aged
@article{Koerte2016,
title = {Cavum Septi Pellucidi in Symptomatic Former Professional Football Players},
author = {Koerte, I K and Hufschmidt, J and Muehlmann, M and Tripodis, Y and Stamm, J M and Pasternak, O and Giwerc, M Y and Coleman, M J and Baugh, C M and Fritts, N G and Heinen, F and Lin, A and Stern, R A and Shenton, M E},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neurotrauma},
volume = {33},
number = {4},
pages = {346--353},
abstract = {Post-mortem studies reveal a high rate of cavum septi pellucidi (CSP) in chronic traumatic encephalopathy (CTE). It remains, however, to be determined whether or not the presence of CSP may be a potential in vivo imaging marker in populations at high risk to develop CTE. The aim of this study was to evaluate CSP in former professional American football players presenting with cognitive and behavioral symptoms compared with noncontact sports athletes. Seventy-two symptomatic former professional football players (mean age 54.53 years, standard deviation [SD] 7.97) as well as 14 former professional noncontact sports athletes (mean age 57.14 years, SD 7.35) underwent high-resolution structural 3T magnetic resonance imaging. Two raters independently evaluated the CSP, and interrater reliability was calculated. Within National Football League players, an association of CSP measures with cognitive and behavioral functioning was evaluated using a multivariate mixed effects model. The measurements of the two raters were highly correlated (CSP length: rho = 0.98; Intraclass Correlation Coefficient [ICC] 0.99; p \< 0.0001; septum length: rho = 0.93; ICC 0.96; p \< 0.0001). For presence versus absence of CSP, there was high agreement (Cohen kappa = 0.83, p \< 0.0001). A higher rate of CSP, a greater length of CSP, as well as a greater ratio of CSP length to septum length was found in symptomatic former professional football players compared with athlete controls. In addition, a greater length of CSP was associated with decreased performance on a list learning task (Neuropsychological Assessment Battery List A Immediate Recall},
keywords = {*Athletes, *Football/in [Injuries], *Septum Pellucidum/pa [Pathology], adult, aged, Brain Concussion/di [Diagnosis], Brain Concussion/ep [Epidemiology], Humans, Male, middle aged},
pubstate = {published},
tppubtype = {article}
}
Bachynski, K E
Tolerable Risks? Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 5, pp. 405–407, 2016.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Adolescent, Brain Concussion/et [Etiology], Child, Craniocerebral Trauma/et [Etiology], Craniocerebral Trauma/pc [Prevention & Control], Head Protective Devices, Humans, Medical, pediatrics, Societies, UNITED States
@article{Bachynski2016,
title = {Tolerable Risks? Physicians and Youth Tackle Football},
author = {Bachynski, K E},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {5},
pages = {405--407},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Adolescent, Brain Concussion/et [Etiology], Child, Craniocerebral Trauma/et [Etiology], Craniocerebral Trauma/pc [Prevention \& Control], Head Protective Devices, Humans, Medical, pediatrics, Societies, UNITED States},
pubstate = {published},
tppubtype = {article}
}
Bachynski, K E
Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 21, pp. 2098, 2016.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans
@article{Bachynski2016b,
title = {Physicians and Youth Tackle Football},
author = {Bachynski, K E},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {21},
pages = {2098},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans},
pubstate = {published},
tppubtype = {article}
}
Larrabee, G J; Rohling, M L; Binder, L M
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007–1008, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Larrabee2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Larrabee, G J and Rohling, M L and Binder, L M},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007--1008},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Stern, R A; Stamm, J M
Author Response Journal Article
In: Neurology, vol. 85, no. 11, pp. 1008–1010, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Stern2015,
title = {Author Response},
author = {Stern, R A and Stamm, J M},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1008--1010},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {*Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]},
pubstate = {published},
tppubtype = {article}
}
Laws, J
The Bright Spotlight on Pro Football Concussions Journal Article
In: Occupational Health & Safety, vol. 84, no. 10, pp. 4, 2015.
BibTeX | Tags: *Brain Concussion/et [Etiology], *Football/in [Injuries], *Motion Pictures as Topic, Brain Concussion/di [Diagnosis], Brain Concussion/th [Therapy], CANADA, Humans, UNITED States
@article{Laws2015,
title = {The Bright Spotlight on Pro Football Concussions},
author = {Laws, J},
year = {2015},
date = {2015-01-01},
journal = {Occupational Health \& Safety},
volume = {84},
number = {10},
pages = {4},
keywords = {*Brain Concussion/et [Etiology], *Football/in [Injuries], *Motion Pictures as Topic, Brain Concussion/di [Diagnosis], Brain Concussion/th [Therapy], CANADA, Humans, UNITED States},
pubstate = {published},
tppubtype = {article}
}
Guthrie, R M
Emerging data on the incidence of concussion in football practice at all levels of amateur play Journal Article
In: Physician & Sportsmedicine, vol. 43, no. 4, pp. 333–335, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male
@article{Guthrie2015,
title = {Emerging data on the incidence of concussion in football practice at all levels of amateur play},
author = {Guthrie, R M},
year = {2015},
date = {2015-01-01},
journal = {Physician \& Sportsmedicine},
volume = {43},
number = {4},
pages = {333--335},
abstract = {There has been increasing concern, particularly in the US, about potential long-term neurological deterioration syndromes seen in the US football players. Recurrent concussions are a potential area of concern. The authors of this paper have used data bases from three levels of amateur US football to identify the rate and risk of concussion injury in both football games and practice at the youth, high school, and college levels. This information is very important initial data around concussion rates at these levels.},
keywords = {*Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Svaldi, D O; Joshi, C; Robinson, M E; Shenk, T E; Abbas, K; Nauman, E A; Leverenz, L J; Talavage, T M
Cerebrovascular reactivity alterations in asymptomatic high school football players Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 80–84, 2015.
Abstract | BibTeX | Tags: *Athletes, *Brain Concussion/pp [Physiopathology], *Brain Injury, *Cerebrovascular Disorders/pp [Physiopathology], *Football/in [Injuries], Adolescent, Chronic/pp [Physiopathology], Humans, RISK assessment, Schools
@article{Svaldi2015,
title = {Cerebrovascular reactivity alterations in asymptomatic high school football players},
author = {Svaldi, D O and Joshi, C and Robinson, M E and Shenk, T E and Abbas, K and Nauman, E A and Leverenz, L J and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {80--84},
abstract = {Cerebrovascular reactivity (CVR) is impaired following brain injury, increasing susceptibility to subsequent injury. CVR was tracked in football and non-collision athletes throughout one season. CVR transiently decreased in football athletes during the first half of the season. Results indicate the brain adapts slowly to increases in loading, increasing risk for injury.},
keywords = {*Athletes, *Brain Concussion/pp [Physiopathology], *Brain Injury, *Cerebrovascular Disorders/pp [Physiopathology], *Football/in [Injuries], Adolescent, Chronic/pp [Physiopathology], Humans, RISK assessment, Schools},
pubstate = {published},
tppubtype = {article}
}
Rogers, L A
Let the Kids Play Football! Journal Article
In: North Carolina Medical Journal, vol. 76, no. 4, pp. 272, 2015.
BibTeX | Tags: *Brain Concussion/et [Etiology], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], Adolescent, Child, Humans, UNITED States
@article{Rogers2015b,
title = {Let the Kids Play Football!},
author = {Rogers, L A},
year = {2015},
date = {2015-01-01},
journal = {North Carolina Medical Journal},
volume = {76},
number = {4},
pages = {272},
keywords = {*Brain Concussion/et [Etiology], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], Adolescent, Child, Humans, UNITED States},
pubstate = {published},
tppubtype = {article}
}
Swartz, E E; Broglio, S P; Cook, S B; Cantu, R C; Ferrara, M S; Guskiewicz, K M; Myers, J L
Early Results of a Helmetless-Tackling Intervention to Decrease Head Impacts in Football Players Journal Article
In: Journal of Athletic Training, vol. 50, no. 12, pp. 1219–1222, 2015.
Abstract | BibTeX | Tags: *Craniocerebral Trauma/pc [Prevention & Control], *Football/in [Injuries], *Physical Education and Training/mt [Methods], Acceleration, Head Protective Devices, Humans, Male, Prospective Studies, Universities
@article{Swartz2015,
title = {Early Results of a Helmetless-Tackling Intervention to Decrease Head Impacts in Football Players},
author = {Swartz, E E and Broglio, S P and Cook, S B and Cantu, R C and Ferrara, M S and Guskiewicz, K M and Myers, J L},
year = {2015},
date = {2015-01-01},
journal = {Journal of Athletic Training},
volume = {50},
number = {12},
pages = {1219--1222},
abstract = {OBJECTIVE: To test a helmetless-tackling behavioral intervention for reducing head impacts in National Collegiate Athletic Association Division I football players. DESIGN: Randomized controlled clinical trial. SETTING: Football field. PATIENTS OR OTHER PARTICIPANTS: Fifty collegiate football players (intervention = 25},
keywords = {*Craniocerebral Trauma/pc [Prevention \& Control], *Football/in [Injuries], *Physical Education and Training/mt [Methods], Acceleration, Head Protective Devices, Humans, Male, Prospective Studies, Universities},
pubstate = {published},
tppubtype = {article}
}
Nauman, E A; Breedlove, K M; Breedlove, E L; Talavage, T M; Robinson, M E; Leverenz, L J
Post-Season Neurophysiological Deficits Assessed by ImPACT and fMRI in Athletes Competing in American Football Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 85–91, 2015.
Abstract | BibTeX | Tags: *Athletes, *Brain Concussion/pp [Physiopathology], *Football/in [Injuries], *MAGNETIC resonance imaging, Adolescent, Brain Concussion/pa [Pathology], Head, Humans, Male, Neurophysiology, Neuropsychological Tests, Schools, Seasons, Surveys and Questionnaires, UNITED States, Young Adult
@article{Nauman2015,
title = {Post-Season Neurophysiological Deficits Assessed by ImPACT and fMRI in Athletes Competing in American Football},
author = {Nauman, E A and Breedlove, K M and Breedlove, E L and Talavage, T M and Robinson, M E and Leverenz, L J},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {85--91},
abstract = {Neurocognitive assessment, functional magnetic resonance imaging, and head impact monitoring were used to evaluate neurological changes in high school football players throughout competitive seasons. A substantial number of asymptomatic athletes exhibited neurophysiological changes that persisted post-season, with abnormal measures significantly more common in athletes receiving 50 or more hits per week during the season.},
keywords = {*Athletes, *Brain Concussion/pp [Physiopathology], *Football/in [Injuries], *MAGNETIC resonance imaging, Adolescent, Brain Concussion/pa [Pathology], Head, Humans, Male, Neurophysiology, Neuropsychological Tests, Schools, Seasons, Surveys and Questionnaires, UNITED States, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Maroon, J C; Bailes, J; Collins, M; Lovell, M; Mathyssek, C
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Maroon2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Maroon, J C and Bailes, J and Collins, M and Lovell, M and Mathyssek, C},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Orchard, J W
Match of the decade: risk management of concussion versus high-speed collisions in the football codes Journal Article
In: Medical Journal of Australia, vol. 203, no. 7, pp. 281–282, 2015.
BibTeX | Tags: *Athletic Injuries/cl [Classification], *Athletic Injuries/di [Diagnosis], *Brain Concussion/cl [Classification], *Brain Concussion/di [Diagnosis], *Football/in [Injuries], Humans, Injury Severity Score, Male, Risk Factors
@article{Orchard2015,
title = {Match of the decade: risk management of concussion versus high-speed collisions in the football codes},
author = {Orchard, J W},
year = {2015},
date = {2015-01-01},
journal = {Medical Journal of Australia},
volume = {203},
number = {7},
pages = {281--282},
keywords = {*Athletic Injuries/cl [Classification], *Athletic Injuries/di [Diagnosis], *Brain Concussion/cl [Classification], *Brain Concussion/di [Diagnosis], *Football/in [Injuries], Humans, Injury Severity Score, Male, Risk Factors},
pubstate = {published},
tppubtype = {article}
}
Wandling, M W; Guillamondegui, O D
Eliminating the Confusion Surrounding Concussions in Sports Journal Article
In: JAMA, vol. 314, no. 13, pp. 1388–1389, 2015.
BibTeX | Tags: *Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male
@article{Wandling2015,
title = {Eliminating the Confusion Surrounding Concussions in Sports},
author = {Wandling, M W and Guillamondegui, O D},
year = {2015},
date = {2015-01-01},
journal = {JAMA},
volume = {314},
number = {13},
pages = {1388--1389},
keywords = {*Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Pham, H; Zemek, R
A 15-year-old rugby player with a head injury Journal Article
In: CMAJ Canadian Medical Association Journal, vol. 187, no. 3, pp. 200–202, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Football/in [Injuries], Adolescent, Athletic Injuries/di [Diagnosis], Athletic Injuries/rh [Rehabilitation], Brain Concussion/ra [Radiography], Brain Concussion/rh [Rehabilitation], Brain Concussion/th [Therapy], Female, Glasgow Coma Scale, Humans, Physical Examination, Recovery of Function, Tomography, X-Ray Computed
@article{Pham2015,
title = {A 15-year-old rugby player with a head injury},
author = {Pham, H and Zemek, R},
year = {2015},
date = {2015-01-01},
journal = {CMAJ Canadian Medical Association Journal},
volume = {187},
number = {3},
pages = {200--202},
keywords = {*Brain Concussion/di [Diagnosis], *Football/in [Injuries], Adolescent, Athletic Injuries/di [Diagnosis], Athletic Injuries/rh [Rehabilitation], Brain Concussion/ra [Radiography], Brain Concussion/rh [Rehabilitation], Brain Concussion/th [Therapy], Female, Glasgow Coma Scale, Humans, Physical Examination, Recovery of Function, Tomography, X-Ray Computed},
pubstate = {published},
tppubtype = {article}
}
Andrikopoulos, J
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Andrikopoulos2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Andrikopoulos, J},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Freitag, A; Kirkwood, G; Scharer, S; Ofori-Asenso, R; Pollock, A M
Systematic review of rugby injuries in children and adolescents under 21 years Journal Article
In: British Journal of Sports Medicine, vol. 49, no. 8, pp. 511–519, 2015.
Abstract | BibTeX | Tags: *Football/in [Injuries], Absenteeism, Adolescent, Athletic Injuries/ep [Epidemiology], Brain Concussion/ep [Epidemiology], Child, Contusions/ep [Epidemiology], Craniocerebral Trauma/ep [Epidemiology], Dislocations/ep [Epidemiology], Extremities/in [Injuries], Female, Hematoma/ep [Epidemiology], Humans, Incidence, Lacerations/ep [Epidemiology], Male, Neck Injuries/ep [Epidemiology], RISK assessment, Sprains and Strains/ep [Epidemiology], Torso/in [Injuries], Young Adult
@article{Freitag2015a,
title = {Systematic review of rugby injuries in children and adolescents under 21 years},
author = {Freitag, A and Kirkwood, G and Scharer, S and Ofori-Asenso, R and Pollock, A M},
year = {2015},
date = {2015-01-01},
journal = {British Journal of Sports Medicine},
volume = {49},
number = {8},
pages = {511--519},
abstract = {A systematic review of rugby union and league injuries among players under the age of 21 years was carried out to calculate probabilities of match injury for a player over a season and a pooled estimate of match injury incidence where studies were sufficiently similar. The probability of a player being injured over a season ranged from 6% to 90% for rugby union and 68% to 96% for rugby league. The pooled injury incidence estimate for rugby union was 26.7/1000 player-hours for injuries irrespective of need for medical attention or time-loss and 10.3/1000 player-hours for injuries requiring at least 7 days absence from games; equivalent to a 28.4% and 12.1% risk of being injured over a season. Study heterogeneity contributed to a wide variation in injury incidence. Public injury surveillance and prevention systems have been successful in reducing injury rates in other countries. No such system exists in the UK. Copyright Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.},
keywords = {*Football/in [Injuries], Absenteeism, Adolescent, Athletic Injuries/ep [Epidemiology], Brain Concussion/ep [Epidemiology], Child, Contusions/ep [Epidemiology], Craniocerebral Trauma/ep [Epidemiology], Dislocations/ep [Epidemiology], Extremities/in [Injuries], Female, Hematoma/ep [Epidemiology], Humans, Incidence, Lacerations/ep [Epidemiology], Male, Neck Injuries/ep [Epidemiology], RISK assessment, Sprains and Strains/ep [Epidemiology], Torso/in [Injuries], Young Adult},
pubstate = {published},
tppubtype = {article}
}
Wood, H
Traumatic brain injury: Cerebral blood flow is linked to sports-related concussion outcomes Journal Article
In: Nature Reviews Neurology, vol. 11, no. 4, pp. 185, 2015.
BibTeX | Tags: *Brain Concussion/pp [Physiopathology], *Cerebral Cortex, *Cerebrovascular Circulation/ph [Physiology], *Football/in [Injuries], *Recovery of Function/ph [Physiology], Humans, Male
@article{Wood2015a,
title = {Traumatic brain injury: Cerebral blood flow is linked to sports-related concussion outcomes},
author = {Wood, H},
year = {2015},
date = {2015-01-01},
journal = {Nature Reviews Neurology},
volume = {11},
number = {4},
pages = {185},
keywords = {*Brain Concussion/pp [Physiopathology], *Cerebral Cortex, *Cerebrovascular Circulation/ph [Physiology], *Football/in [Injuries], *Recovery of Function/ph [Physiology], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Myer, G D; Smith, D; Foss, K D; DiCesare, C A; Kiefer, A W; Kushner, A M; Thomas, S M; Sucharew, H; Khoury, J C
Response Journal Article
In: Journal of Orthopaedic & Sports Physical Therapy, vol. 44, no. 6, pp. 459–460, 2014.
BibTeX | Tags: *Altitude, *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male
@article{Myer2014a,
title = {Response},
author = {Myer, G D and Smith, D and Foss, K D and DiCesare, C A and Kiefer, A W and Kushner, A M and Thomas, S M and Sucharew, H and Khoury, J C},
year = {2014},
date = {2014-01-01},
journal = {Journal of Orthopaedic \& Sports Physical Therapy},
volume = {44},
number = {6},
pages = {459--460},
keywords = {*Altitude, *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Rowson, S; Duma, S M; Greenwald, R M; Beckwith, J G; Guskiewicz, K M; Crisco, J J; Wilcox, B J; McAllister, T W; Maerlender, A C; Broglio, S P; Schnebel, B; Brolinson, P G
Response Journal Article
In: Journal of Neurosurgery, vol. 121, no. 2, pp. 492–493, 2014.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Head Protective Devices, Humans, Male
@article{Rowson2014a,
title = {Response},
author = {Rowson, S and Duma, S M and Greenwald, R M and Beckwith, J G and Guskiewicz, K M and Crisco, J J and Wilcox, B J and McAllister, T W and Maerlender, A C and Broglio, S P and Schnebel, B and Brolinson, P G},
year = {2014},
date = {2014-01-01},
journal = {Journal of Neurosurgery},
volume = {121},
number = {2},
pages = {492--493},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Head Protective Devices, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Beckwith, J G; Greenwald, R M; Chu, J J; Crisco, J J; Rowson, S; Duma, S M; Broglio, S P; McAllister, T W; Guskiewicz, K M; Mihalik, J P; Anderson, S; Schnebel, B; Brolinson, P G; Collins, M W
Timing of concussion diagnosis is related to head impact exposure prior to injury Journal Article
In: Medicine & Science in Sports & Exercise, vol. 45, no. 4, pp. 747–754, 2013.
Abstract | BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/et [Etiology], *Delayed Diagnosis, *Football/in [Injuries], *HEAD injuries, Adolescent, Closed/ep [Epidemiology], ENVIRONMENTAL exposure, Head Protective Devices, Humans, Male, Telemetry/is [Instrumentation], Time Factors, Young Adult
@article{Beckwith2013a,
title = {Timing of concussion diagnosis is related to head impact exposure prior to injury},
author = {Beckwith, J G and Greenwald, R M and Chu, J J and Crisco, J J and Rowson, S and Duma, S M and Broglio, S P and McAllister, T W and Guskiewicz, K M and Mihalik, J P and Anderson, S and Schnebel, B and Brolinson, P G and Collins, M W},
year = {2013},
date = {2013-01-01},
journal = {Medicine \& Science in Sports \& Exercise},
volume = {45},
number = {4},
pages = {747--754},
abstract = {PURPOSE: Concussions are commonly undiagnosed in an athletic environment because the postinjury signs and symptoms may be mild, masked by the subject, or unrecognized. This study compares measures of head impact frequency, location, and kinematic response before cases of immediate and delayed concussion diagnosis. METHODS: Football players from eight collegiate and six high school teams wore instrumented helmets during play (n = 1208), of which 95 were diagnosed with concussion (105 total cases). Acceleration data recorded by the instrumented helmets were reduced to five kinematic metrics: peak linear and rotational acceleration, Gadd severity index, head injury criterion, and change in head velocity (DELTAv). In addition, each impact was assigned to one of four general location regions (front, back, side, and top), and the number of impacts sustained before injury was calculated over two periods (1 and 7 days). RESULTS: All head kinematic measures associated with injury, except peak rotational acceleration (P = 0.284), were significantly higher for cases of immediate diagnosis than delayed diagnosis (P \< 0.05). Players with delayed diagnosis sustained a significantly higher number of head impacts on the day of injury (32.9 +/- 24.9, P \< 0.001) and within 7 d of injury (69.7 +/- 43.3},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/et [Etiology], *Delayed Diagnosis, *Football/in [Injuries], *HEAD injuries, Adolescent, Closed/ep [Epidemiology], ENVIRONMENTAL exposure, Head Protective Devices, Humans, Male, Telemetry/is [Instrumentation], Time Factors, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Thornton, A E; Cox, D N; Whitfield, K; Fouladi, R T
Cumulative concussion exposure in rugby players: neurocognitive and symptomatic outcomes Journal Article
In: Journal of Clinical & Experimental Neuropsychology, vol. 30, no. 4, pp. 398–409, 2008.
Abstract | BibTeX | Tags: *Brain Concussion/co [Complications], *COGNITION, *Cognition Disorders/et [Etiology], *Football/in [Injuries], adult, Age Factors, aged, Brain Concussion/di [Diagnosis], Female, Humans, Male, middle aged, Neuropsychological Tests, Predictive Value of Tests, REGRESSION analysis, Surveys and Questionnaires, Trauma Severity Indices
@article{Thornton2008a,
title = {Cumulative concussion exposure in rugby players: neurocognitive and symptomatic outcomes},
author = {Thornton, A E and Cox, D N and Whitfield, K and Fouladi, R T},
year = {2008},
date = {2008-01-01},
journal = {Journal of Clinical \& Experimental Neuropsychology},
volume = {30},
number = {4},
pages = {398--409},
abstract = {A total of 111 rugby players underwent comprehensive testing to determine the impact of self-reported concussion exposure. Reliable estimates of concussion exposure were associated with an increase in postconcussion symptoms (PCS), but not diminished neurocognitive functioning. Importantly, the effects of concussion exposure on PCS varied as a function of player status. More specifically, extent of concussion exposure was associated with increased memory complaints and overall PCS endorsements in a dose-dependent manner for retired and older recreational players, but not for those who were younger and playing at more competitive levels. Future work should systematically evaluate the constituent participant factors that may influence differential concussion outcomes.},
keywords = {*Brain Concussion/co [Complications], *COGNITION, *Cognition Disorders/et [Etiology], *Football/in [Injuries], adult, Age Factors, aged, Brain Concussion/di [Diagnosis], Female, Humans, Male, middle aged, Neuropsychological Tests, Predictive Value of Tests, REGRESSION analysis, Surveys and Questionnaires, Trauma Severity Indices},
pubstate = {published},
tppubtype = {article}
}
Stewart, W; McNamara, P H; Lawlor, B; Hutchinson, S; Farrell, M
Chronic traumatic encephalopathy: a potential late and under recognized consequence of rugby union? Journal Article
In: Qjm, vol. 109, no. 1, pp. 11–15, 2016.
@article{Stewart2016,
title = {Chronic traumatic encephalopathy: a potential late and under recognized consequence of rugby union?},
author = {Stewart, W and McNamara, P H and Lawlor, B and Hutchinson, S and Farrell, M},
year = {2016},
date = {2016-01-01},
journal = {Qjm},
volume = {109},
number = {1},
pages = {11--15},
abstract = {The association between exposure to head injury and increased risk of neurodegenerative disease, specifically chronic traumatic encephalopathy (CTE), is widely recognized. Historically, this was largely considered a phenomenon restricted to boxers, with more recent case series identifying further 'high risk' individuals, such as former American footballers, or military personnel. However, in all cases thus far reported, it is clear that it is the exposure to head injury which is associated with increased dementia risk, and not the circumstances or environment of exposure. As such, there is considerable potential for under-recognition of CTE in patients presenting with neurodegenerative disease, particularly where head injury exposure might have been historical and through sport. This article reviews current understanding of CTE and, via an illustrative case in rugby union, highlights the value of a detailed history on head injury and also draws attention to imaging studies in assessing patients with neurodegenerative disease. Copyright © The Author 2015. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Auerbach, P S; Waggoner 2nd, W H
It's Time to Change the Rules Journal Article
In: JAMA, vol. 316, no. 12, pp. 1260–1261, 2016.
@article{Auerbach2016,
title = {It's Time to Change the Rules},
author = {Auerbach, P S and {Waggoner 2nd}, W H},
year = {2016},
date = {2016-01-01},
journal = {JAMA},
volume = {316},
number = {12},
pages = {1260--1261},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
McCarthy, M
Undercounting of football concussions skewed NFL research, US investigation alleges Journal Article
In: BMJ, vol. 352, pp. i1788, 2016.
@article{McCarthy2016b,
title = {Undercounting of football concussions skewed NFL research, US investigation alleges},
author = {McCarthy, M},
year = {2016},
date = {2016-01-01},
journal = {BMJ},
volume = {352},
pages = {i1788},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Lucke-Wold, B P; Turner, R C; Logsdon, A F; Nguyen, L; Bailes, J E; Lee, J M; Robson, M J; Omalu, B I; Huber, J D; Rosen, C L
Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy Journal Article
In: Journal of Neurosurgery, vol. 124, no. 3, pp. 687–702, 2016.
@article{Lucke-Wold2016,
title = {Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy},
author = {Lucke-Wold, B P and Turner, R C and Logsdon, A F and Nguyen, L and Bailes, J E and Lee, J M and Robson, M J and Omalu, B I and Huber, J D and Rosen, C L},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neurosurgery},
volume = {124},
number = {3},
pages = {687--702},
abstract = {OBJECTIVE: Chronic traumatic encephalopathy is a progressive neurodegenerative disease characterized by neurofibrillary tau tangles following repetitive neurotrauma. The underlying mechanism linking traumatic brain injury to chronic traumatic encephalopathy has not been elucidated. The authors investigate the role of endoplasmic reticulum stress as a link between acute neurotrauma and chronic neurodegeneration. METHODS: The authors used pharmacological, biochemical, and behavioral tools to assess the role of endoplasmic reticulum stress in linking acute repetitive traumatic brain injury to the development of chronic neurodegeneration. Data from the authors' clinically relevant and validated rodent blast model were compared with those obtained from postmortem human chronic traumatic encephalopathy specimens from a National Football League player and World Wrestling Entertainment wrestler. RESULTS: The results demonstrated strong correlation of endoplasmic reticulum stress activation with subsequent tau hyperphosphorylation. Various endoplasmic reticulum stress markers were increased in human chronic traumatic encephalopathy specimens, and the endoplasmic reticulum stress response was associated with an increase in the tau kinase, glycogen synthase kinase-3beta. Docosahexaenoic acid, an endoplasmic reticulum stress inhibitor, improved cognitive performance in the rat model 3 weeks after repetitive blast exposure. The data showed that docosahexaenoic acid administration substantially reduced tau hyperphosphorylation (t = 4.111, p \< 0.05), improved cognition (t = 6.532, p \< 0.001), and inhibited C/EBP homology protein activation (t = 5.631, p \< 0.01). Additionally the data showed, for the first time, that endoplasmic reticulum stress is involved in the pathophysiology of chronic traumatic encephalopathy. CONCLUSIONS: Docosahexaenoic acid therefore warrants further investigation as a potential therapeutic agent for the prevention of chronic traumatic encephalopathy.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Iverson, G L
Suicide and Chronic Traumatic Encephalopathy Journal Article
In: Journal of Neuropsychiatry & Clinical Neurosciences, vol. 28, no. 1, pp. 9–16, 2016.
@article{Iverson2016a,
title = {Suicide and Chronic Traumatic Encephalopathy},
author = {Iverson, G L},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neuropsychiatry \& Clinical Neurosciences},
volume = {28},
number = {1},
pages = {9--16},
abstract = {For nearly 80 years, suicidality was not considered to be a core clinical feature of chronic traumatic encephalopathy (CTE). In recent years, suicide has been widely cited as being associated with CTE, and now depression has been proposed to be one of three core diagnostic features alongside cognitive impairment and anger control problems. This evolution of the clinical features has been reinforced by thousands of media stories reporting a connection between mental health problems in former athletes and military veterans, repetitive neurotrauma, and CTE. At present, the science underlying the causal assumption between repetitive neurotrauma, depression, suicide, and the neuropathology believed to be unique to CTE is inconclusive. Epidemiological evidence indicates that former National Football League players, for example, are at lower, not greater, risk for suicide than men in the general population. This article aims to discuss the critical issues and literature relating to these possible relationships.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Samadani, U
Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 21, pp. 2097–2098, 2016.
@article{Samadani2016,
title = {Physicians and Youth Tackle Football},
author = {Samadani, U},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {21},
pages = {2097--2098},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Koerte, I K; Hufschmidt, J; Muehlmann, M; Tripodis, Y; Stamm, J M; Pasternak, O; Giwerc, M Y; Coleman, M J; Baugh, C M; Fritts, N G; Heinen, F; Lin, A; Stern, R A; Shenton, M E
Cavum Septi Pellucidi in Symptomatic Former Professional Football Players Journal Article
In: Journal of Neurotrauma, vol. 33, no. 4, pp. 346–353, 2016.
@article{Koerte2016,
title = {Cavum Septi Pellucidi in Symptomatic Former Professional Football Players},
author = {Koerte, I K and Hufschmidt, J and Muehlmann, M and Tripodis, Y and Stamm, J M and Pasternak, O and Giwerc, M Y and Coleman, M J and Baugh, C M and Fritts, N G and Heinen, F and Lin, A and Stern, R A and Shenton, M E},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neurotrauma},
volume = {33},
number = {4},
pages = {346--353},
abstract = {Post-mortem studies reveal a high rate of cavum septi pellucidi (CSP) in chronic traumatic encephalopathy (CTE). It remains, however, to be determined whether or not the presence of CSP may be a potential in vivo imaging marker in populations at high risk to develop CTE. The aim of this study was to evaluate CSP in former professional American football players presenting with cognitive and behavioral symptoms compared with noncontact sports athletes. Seventy-two symptomatic former professional football players (mean age 54.53 years, standard deviation [SD] 7.97) as well as 14 former professional noncontact sports athletes (mean age 57.14 years, SD 7.35) underwent high-resolution structural 3T magnetic resonance imaging. Two raters independently evaluated the CSP, and interrater reliability was calculated. Within National Football League players, an association of CSP measures with cognitive and behavioral functioning was evaluated using a multivariate mixed effects model. The measurements of the two raters were highly correlated (CSP length: rho = 0.98; Intraclass Correlation Coefficient [ICC] 0.99; p \< 0.0001; septum length: rho = 0.93; ICC 0.96; p \< 0.0001). For presence versus absence of CSP, there was high agreement (Cohen kappa = 0.83, p \< 0.0001). A higher rate of CSP, a greater length of CSP, as well as a greater ratio of CSP length to septum length was found in symptomatic former professional football players compared with athlete controls. In addition, a greater length of CSP was associated with decreased performance on a list learning task (Neuropsychological Assessment Battery List A Immediate Recall},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Bachynski, K E
Tolerable Risks? Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 5, pp. 405–407, 2016.
@article{Bachynski2016,
title = {Tolerable Risks? Physicians and Youth Tackle Football},
author = {Bachynski, K E},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {5},
pages = {405--407},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Bachynski, K E
Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 21, pp. 2098, 2016.
@article{Bachynski2016b,
title = {Physicians and Youth Tackle Football},
author = {Bachynski, K E},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {21},
pages = {2098},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Larrabee, G J; Rohling, M L; Binder, L M
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007–1008, 2015.
@article{Larrabee2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Larrabee, G J and Rohling, M L and Binder, L M},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007--1008},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Stern, R A; Stamm, J M
Author Response Journal Article
In: Neurology, vol. 85, no. 11, pp. 1008–1010, 2015.
@article{Stern2015,
title = {Author Response},
author = {Stern, R A and Stamm, J M},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1008--1010},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Laws, J
The Bright Spotlight on Pro Football Concussions Journal Article
In: Occupational Health & Safety, vol. 84, no. 10, pp. 4, 2015.
@article{Laws2015,
title = {The Bright Spotlight on Pro Football Concussions},
author = {Laws, J},
year = {2015},
date = {2015-01-01},
journal = {Occupational Health \& Safety},
volume = {84},
number = {10},
pages = {4},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Guthrie, R M
Emerging data on the incidence of concussion in football practice at all levels of amateur play Journal Article
In: Physician & Sportsmedicine, vol. 43, no. 4, pp. 333–335, 2015.
@article{Guthrie2015,
title = {Emerging data on the incidence of concussion in football practice at all levels of amateur play},
author = {Guthrie, R M},
year = {2015},
date = {2015-01-01},
journal = {Physician \& Sportsmedicine},
volume = {43},
number = {4},
pages = {333--335},
abstract = {There has been increasing concern, particularly in the US, about potential long-term neurological deterioration syndromes seen in the US football players. Recurrent concussions are a potential area of concern. The authors of this paper have used data bases from three levels of amateur US football to identify the rate and risk of concussion injury in both football games and practice at the youth, high school, and college levels. This information is very important initial data around concussion rates at these levels.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Svaldi, D O; Joshi, C; Robinson, M E; Shenk, T E; Abbas, K; Nauman, E A; Leverenz, L J; Talavage, T M
Cerebrovascular reactivity alterations in asymptomatic high school football players Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 80–84, 2015.
@article{Svaldi2015,
title = {Cerebrovascular reactivity alterations in asymptomatic high school football players},
author = {Svaldi, D O and Joshi, C and Robinson, M E and Shenk, T E and Abbas, K and Nauman, E A and Leverenz, L J and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {80--84},
abstract = {Cerebrovascular reactivity (CVR) is impaired following brain injury, increasing susceptibility to subsequent injury. CVR was tracked in football and non-collision athletes throughout one season. CVR transiently decreased in football athletes during the first half of the season. Results indicate the brain adapts slowly to increases in loading, increasing risk for injury.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Rogers, L A
Let the Kids Play Football! Journal Article
In: North Carolina Medical Journal, vol. 76, no. 4, pp. 272, 2015.
@article{Rogers2015b,
title = {Let the Kids Play Football!},
author = {Rogers, L A},
year = {2015},
date = {2015-01-01},
journal = {North Carolina Medical Journal},
volume = {76},
number = {4},
pages = {272},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Swartz, E E; Broglio, S P; Cook, S B; Cantu, R C; Ferrara, M S; Guskiewicz, K M; Myers, J L
Early Results of a Helmetless-Tackling Intervention to Decrease Head Impacts in Football Players Journal Article
In: Journal of Athletic Training, vol. 50, no. 12, pp. 1219–1222, 2015.
@article{Swartz2015,
title = {Early Results of a Helmetless-Tackling Intervention to Decrease Head Impacts in Football Players},
author = {Swartz, E E and Broglio, S P and Cook, S B and Cantu, R C and Ferrara, M S and Guskiewicz, K M and Myers, J L},
year = {2015},
date = {2015-01-01},
journal = {Journal of Athletic Training},
volume = {50},
number = {12},
pages = {1219--1222},
abstract = {OBJECTIVE: To test a helmetless-tackling behavioral intervention for reducing head impacts in National Collegiate Athletic Association Division I football players. DESIGN: Randomized controlled clinical trial. SETTING: Football field. PATIENTS OR OTHER PARTICIPANTS: Fifty collegiate football players (intervention = 25},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Nauman, E A; Breedlove, K M; Breedlove, E L; Talavage, T M; Robinson, M E; Leverenz, L J
Post-Season Neurophysiological Deficits Assessed by ImPACT and fMRI in Athletes Competing in American Football Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 85–91, 2015.
@article{Nauman2015,
title = {Post-Season Neurophysiological Deficits Assessed by ImPACT and fMRI in Athletes Competing in American Football},
author = {Nauman, E A and Breedlove, K M and Breedlove, E L and Talavage, T M and Robinson, M E and Leverenz, L J},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {85--91},
abstract = {Neurocognitive assessment, functional magnetic resonance imaging, and head impact monitoring were used to evaluate neurological changes in high school football players throughout competitive seasons. A substantial number of asymptomatic athletes exhibited neurophysiological changes that persisted post-season, with abnormal measures significantly more common in athletes receiving 50 or more hits per week during the season.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Maroon, J C; Bailes, J; Collins, M; Lovell, M; Mathyssek, C
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007, 2015.
@article{Maroon2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Maroon, J C and Bailes, J and Collins, M and Lovell, M and Mathyssek, C},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Orchard, J W
Match of the decade: risk management of concussion versus high-speed collisions in the football codes Journal Article
In: Medical Journal of Australia, vol. 203, no. 7, pp. 281–282, 2015.
@article{Orchard2015,
title = {Match of the decade: risk management of concussion versus high-speed collisions in the football codes},
author = {Orchard, J W},
year = {2015},
date = {2015-01-01},
journal = {Medical Journal of Australia},
volume = {203},
number = {7},
pages = {281--282},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Stewart, W; McNamara, P H; Lawlor, B; Hutchinson, S; Farrell, M
Chronic traumatic encephalopathy: a potential late and under recognized consequence of rugby union? Journal Article
In: Qjm, vol. 109, no. 1, pp. 11–15, 2016.
Abstract | BibTeX | Tags: *Brain Concussion/co [Complications], *Brain Injury, *Brain/pp [Physiopathology], *Football/in [Injuries], *Neurodegenerative Diseases/pp [Physiopathology], Chronic/pa [Pathology], Humans, Magnetic Resonance Imaging, Male, middle aged, neurologic examination
@article{Stewart2016,
title = {Chronic traumatic encephalopathy: a potential late and under recognized consequence of rugby union?},
author = {Stewart, W and McNamara, P H and Lawlor, B and Hutchinson, S and Farrell, M},
year = {2016},
date = {2016-01-01},
journal = {Qjm},
volume = {109},
number = {1},
pages = {11--15},
abstract = {The association between exposure to head injury and increased risk of neurodegenerative disease, specifically chronic traumatic encephalopathy (CTE), is widely recognized. Historically, this was largely considered a phenomenon restricted to boxers, with more recent case series identifying further 'high risk' individuals, such as former American footballers, or military personnel. However, in all cases thus far reported, it is clear that it is the exposure to head injury which is associated with increased dementia risk, and not the circumstances or environment of exposure. As such, there is considerable potential for under-recognition of CTE in patients presenting with neurodegenerative disease, particularly where head injury exposure might have been historical and through sport. This article reviews current understanding of CTE and, via an illustrative case in rugby union, highlights the value of a detailed history on head injury and also draws attention to imaging studies in assessing patients with neurodegenerative disease. Copyright © The Author 2015. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.},
keywords = {*Brain Concussion/co [Complications], *Brain Injury, *Brain/pp [Physiopathology], *Football/in [Injuries], *Neurodegenerative Diseases/pp [Physiopathology], Chronic/pa [Pathology], Humans, Magnetic Resonance Imaging, Male, middle aged, neurologic examination},
pubstate = {published},
tppubtype = {article}
}
Auerbach, P S; Waggoner 2nd, W H
It's Time to Change the Rules Journal Article
In: JAMA, vol. 316, no. 12, pp. 1260–1261, 2016.
BibTeX | Tags: *Brain Concussion/co [Complications], *Football/in [Injuries], adult, Brain Concussion/et [Etiology], Brain Concussion/pc [Prevention & Control], Football/st [Standards], Humans, Male, Safety/st [Standards], UNITED States
@article{Auerbach2016,
title = {It's Time to Change the Rules},
author = {Auerbach, P S and {Waggoner 2nd}, W H},
year = {2016},
date = {2016-01-01},
journal = {JAMA},
volume = {316},
number = {12},
pages = {1260--1261},
keywords = {*Brain Concussion/co [Complications], *Football/in [Injuries], adult, Brain Concussion/et [Etiology], Brain Concussion/pc [Prevention \& Control], Football/st [Standards], Humans, Male, Safety/st [Standards], UNITED States},
pubstate = {published},
tppubtype = {article}
}
McCarthy, M
Undercounting of football concussions skewed NFL research, US investigation alleges Journal Article
In: BMJ, vol. 352, pp. i1788, 2016.
BibTeX | Tags: *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Biomedical Research/sn [Statistics & Numerical Dat, Football/sn [Statistics & Numerical Data], Humans, Research Design/sn [Statistics & Numerical Data], United States/ep [Epidemiology]
@article{McCarthy2016b,
title = {Undercounting of football concussions skewed NFL research, US investigation alleges},
author = {McCarthy, M},
year = {2016},
date = {2016-01-01},
journal = {BMJ},
volume = {352},
pages = {i1788},
keywords = {*Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Biomedical Research/sn [Statistics \& Numerical Dat, Football/sn [Statistics \& Numerical Data], Humans, Research Design/sn [Statistics \& Numerical Data], United States/ep [Epidemiology]},
pubstate = {published},
tppubtype = {article}
}
Lucke-Wold, B P; Turner, R C; Logsdon, A F; Nguyen, L; Bailes, J E; Lee, J M; Robson, M J; Omalu, B I; Huber, J D; Rosen, C L
Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy Journal Article
In: Journal of Neurosurgery, vol. 124, no. 3, pp. 687–702, 2016.
Abstract | BibTeX | Tags: *Blast Injuries/px [Psychology], *Brain Injury, *Endoplasmic Reticulum Stress/ph [Physiology], *Football/in [Injuries], *Wrestling/in [Injuries], adult, animal, Animals, Blast Injuries/et [Etiology], Blast Injuries/pa [Pathology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Disease Models, Humans, Male, Rats, Sprague-Dawley
@article{Lucke-Wold2016,
title = {Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy},
author = {Lucke-Wold, B P and Turner, R C and Logsdon, A F and Nguyen, L and Bailes, J E and Lee, J M and Robson, M J and Omalu, B I and Huber, J D and Rosen, C L},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neurosurgery},
volume = {124},
number = {3},
pages = {687--702},
abstract = {OBJECTIVE: Chronic traumatic encephalopathy is a progressive neurodegenerative disease characterized by neurofibrillary tau tangles following repetitive neurotrauma. The underlying mechanism linking traumatic brain injury to chronic traumatic encephalopathy has not been elucidated. The authors investigate the role of endoplasmic reticulum stress as a link between acute neurotrauma and chronic neurodegeneration. METHODS: The authors used pharmacological, biochemical, and behavioral tools to assess the role of endoplasmic reticulum stress in linking acute repetitive traumatic brain injury to the development of chronic neurodegeneration. Data from the authors' clinically relevant and validated rodent blast model were compared with those obtained from postmortem human chronic traumatic encephalopathy specimens from a National Football League player and World Wrestling Entertainment wrestler. RESULTS: The results demonstrated strong correlation of endoplasmic reticulum stress activation with subsequent tau hyperphosphorylation. Various endoplasmic reticulum stress markers were increased in human chronic traumatic encephalopathy specimens, and the endoplasmic reticulum stress response was associated with an increase in the tau kinase, glycogen synthase kinase-3beta. Docosahexaenoic acid, an endoplasmic reticulum stress inhibitor, improved cognitive performance in the rat model 3 weeks after repetitive blast exposure. The data showed that docosahexaenoic acid administration substantially reduced tau hyperphosphorylation (t = 4.111, p \< 0.05), improved cognition (t = 6.532, p \< 0.001), and inhibited C/EBP homology protein activation (t = 5.631, p \< 0.01). Additionally the data showed, for the first time, that endoplasmic reticulum stress is involved in the pathophysiology of chronic traumatic encephalopathy. CONCLUSIONS: Docosahexaenoic acid therefore warrants further investigation as a potential therapeutic agent for the prevention of chronic traumatic encephalopathy.},
keywords = {*Blast Injuries/px [Psychology], *Brain Injury, *Endoplasmic Reticulum Stress/ph [Physiology], *Football/in [Injuries], *Wrestling/in [Injuries], adult, animal, Animals, Blast Injuries/et [Etiology], Blast Injuries/pa [Pathology], Brain Injury, Chronic/et [Etiology], Chronic/pa [Pathology], Chronic/px [Psychology], Disease Models, Humans, Male, Rats, Sprague-Dawley},
pubstate = {published},
tppubtype = {article}
}
Iverson, G L
Suicide and Chronic Traumatic Encephalopathy Journal Article
In: Journal of Neuropsychiatry & Clinical Neurosciences, vol. 28, no. 1, pp. 9–16, 2016.
Abstract | BibTeX | Tags: *Brain Injury, *Football/in [Injuries], *Suicide/px [Psychology], Athletic Injuries/di [Diagnosis], Athletic Injuries/ep [Epidemiology], Athletic Injuries/px [Psychology], Brain Injury, Chronic/di [Diagnosis], Chronic/ep [Epidemiology], Chronic/px [Psychology], Football/px [Psychology], Humans, Male, Risk Factors, Suicide/td [Trends]
@article{Iverson2016a,
title = {Suicide and Chronic Traumatic Encephalopathy},
author = {Iverson, G L},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neuropsychiatry \& Clinical Neurosciences},
volume = {28},
number = {1},
pages = {9--16},
abstract = {For nearly 80 years, suicidality was not considered to be a core clinical feature of chronic traumatic encephalopathy (CTE). In recent years, suicide has been widely cited as being associated with CTE, and now depression has been proposed to be one of three core diagnostic features alongside cognitive impairment and anger control problems. This evolution of the clinical features has been reinforced by thousands of media stories reporting a connection between mental health problems in former athletes and military veterans, repetitive neurotrauma, and CTE. At present, the science underlying the causal assumption between repetitive neurotrauma, depression, suicide, and the neuropathology believed to be unique to CTE is inconclusive. Epidemiological evidence indicates that former National Football League players, for example, are at lower, not greater, risk for suicide than men in the general population. This article aims to discuss the critical issues and literature relating to these possible relationships.},
keywords = {*Brain Injury, *Football/in [Injuries], *Suicide/px [Psychology], Athletic Injuries/di [Diagnosis], Athletic Injuries/ep [Epidemiology], Athletic Injuries/px [Psychology], Brain Injury, Chronic/di [Diagnosis], Chronic/ep [Epidemiology], Chronic/px [Psychology], Football/px [Psychology], Humans, Male, Risk Factors, Suicide/td [Trends]},
pubstate = {published},
tppubtype = {article}
}
Samadani, U
Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 21, pp. 2097–2098, 2016.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans
@article{Samadani2016,
title = {Physicians and Youth Tackle Football},
author = {Samadani, U},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {21},
pages = {2097--2098},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans},
pubstate = {published},
tppubtype = {article}
}
Koerte, I K; Hufschmidt, J; Muehlmann, M; Tripodis, Y; Stamm, J M; Pasternak, O; Giwerc, M Y; Coleman, M J; Baugh, C M; Fritts, N G; Heinen, F; Lin, A; Stern, R A; Shenton, M E
Cavum Septi Pellucidi in Symptomatic Former Professional Football Players Journal Article
In: Journal of Neurotrauma, vol. 33, no. 4, pp. 346–353, 2016.
Abstract | BibTeX | Tags: *Athletes, *Football/in [Injuries], *Septum Pellucidum/pa [Pathology], adult, aged, Brain Concussion/di [Diagnosis], Brain Concussion/ep [Epidemiology], Humans, Male, middle aged
@article{Koerte2016,
title = {Cavum Septi Pellucidi in Symptomatic Former Professional Football Players},
author = {Koerte, I K and Hufschmidt, J and Muehlmann, M and Tripodis, Y and Stamm, J M and Pasternak, O and Giwerc, M Y and Coleman, M J and Baugh, C M and Fritts, N G and Heinen, F and Lin, A and Stern, R A and Shenton, M E},
year = {2016},
date = {2016-01-01},
journal = {Journal of Neurotrauma},
volume = {33},
number = {4},
pages = {346--353},
abstract = {Post-mortem studies reveal a high rate of cavum septi pellucidi (CSP) in chronic traumatic encephalopathy (CTE). It remains, however, to be determined whether or not the presence of CSP may be a potential in vivo imaging marker in populations at high risk to develop CTE. The aim of this study was to evaluate CSP in former professional American football players presenting with cognitive and behavioral symptoms compared with noncontact sports athletes. Seventy-two symptomatic former professional football players (mean age 54.53 years, standard deviation [SD] 7.97) as well as 14 former professional noncontact sports athletes (mean age 57.14 years, SD 7.35) underwent high-resolution structural 3T magnetic resonance imaging. Two raters independently evaluated the CSP, and interrater reliability was calculated. Within National Football League players, an association of CSP measures with cognitive and behavioral functioning was evaluated using a multivariate mixed effects model. The measurements of the two raters were highly correlated (CSP length: rho = 0.98; Intraclass Correlation Coefficient [ICC] 0.99; p \< 0.0001; septum length: rho = 0.93; ICC 0.96; p \< 0.0001). For presence versus absence of CSP, there was high agreement (Cohen kappa = 0.83, p \< 0.0001). A higher rate of CSP, a greater length of CSP, as well as a greater ratio of CSP length to septum length was found in symptomatic former professional football players compared with athlete controls. In addition, a greater length of CSP was associated with decreased performance on a list learning task (Neuropsychological Assessment Battery List A Immediate Recall},
keywords = {*Athletes, *Football/in [Injuries], *Septum Pellucidum/pa [Pathology], adult, aged, Brain Concussion/di [Diagnosis], Brain Concussion/ep [Epidemiology], Humans, Male, middle aged},
pubstate = {published},
tppubtype = {article}
}
Bachynski, K E
Tolerable Risks? Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 5, pp. 405–407, 2016.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Adolescent, Brain Concussion/et [Etiology], Child, Craniocerebral Trauma/et [Etiology], Craniocerebral Trauma/pc [Prevention & Control], Head Protective Devices, Humans, Medical, pediatrics, Societies, UNITED States
@article{Bachynski2016,
title = {Tolerable Risks? Physicians and Youth Tackle Football},
author = {Bachynski, K E},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {5},
pages = {405--407},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Adolescent, Brain Concussion/et [Etiology], Child, Craniocerebral Trauma/et [Etiology], Craniocerebral Trauma/pc [Prevention \& Control], Head Protective Devices, Humans, Medical, pediatrics, Societies, UNITED States},
pubstate = {published},
tppubtype = {article}
}
Bachynski, K E
Physicians and Youth Tackle Football Journal Article
In: New England Journal of Medicine, vol. 374, no. 21, pp. 2098, 2016.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans
@article{Bachynski2016b,
title = {Physicians and Youth Tackle Football},
author = {Bachynski, K E},
year = {2016},
date = {2016-01-01},
journal = {New England Journal of Medicine},
volume = {374},
number = {21},
pages = {2098},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Guidelines as Topic, *Physician's Role, *SPORTS medicine, Humans},
pubstate = {published},
tppubtype = {article}
}
Larrabee, G J; Rohling, M L; Binder, L M
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007–1008, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Larrabee2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Larrabee, G J and Rohling, M L and Binder, L M},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007--1008},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Stern, R A; Stamm, J M
Author Response Journal Article
In: Neurology, vol. 85, no. 11, pp. 1008–1010, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Stern2015,
title = {Author Response},
author = {Stern, R A and Stamm, J M},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1008--1010},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Chun, I Y; Mao, X; Breedlove, E L; Leverenz, L J; Nauman, E A; Talavage, T M
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 92–97, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]
@article{Chun2015,
title = {DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts},
author = {Chun, I Y and Mao, X and Breedlove, E L and Leverenz, L J and Nauman, E A and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {92--97},
abstract = {Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.},
keywords = {*Athletic Injuries/pa [Pathology], *Craniocerebral Trauma/pp [Physiopathology], *Diffusion Magnetic Resonance Imaging/mt [Methods], *Football/in [Injuries], *White Matter/ab [Abnormalities], *White Matter/pp [Physiopathology], Adolescent, Athletes, Brain Concussion/di [Diagnosis], Brain Concussion/pp [Physiopathology], Brain/pp [Physiopathology], Brain/ra [Radiography], Craniocerebral Trauma/di [Diagnosis], Head, Humans, Schools, Time Factors, White Matter/pa [Pathology]},
pubstate = {published},
tppubtype = {article}
}
Laws, J
The Bright Spotlight on Pro Football Concussions Journal Article
In: Occupational Health & Safety, vol. 84, no. 10, pp. 4, 2015.
BibTeX | Tags: *Brain Concussion/et [Etiology], *Football/in [Injuries], *Motion Pictures as Topic, Brain Concussion/di [Diagnosis], Brain Concussion/th [Therapy], CANADA, Humans, UNITED States
@article{Laws2015,
title = {The Bright Spotlight on Pro Football Concussions},
author = {Laws, J},
year = {2015},
date = {2015-01-01},
journal = {Occupational Health \& Safety},
volume = {84},
number = {10},
pages = {4},
keywords = {*Brain Concussion/et [Etiology], *Football/in [Injuries], *Motion Pictures as Topic, Brain Concussion/di [Diagnosis], Brain Concussion/th [Therapy], CANADA, Humans, UNITED States},
pubstate = {published},
tppubtype = {article}
}
Guthrie, R M
Emerging data on the incidence of concussion in football practice at all levels of amateur play Journal Article
In: Physician & Sportsmedicine, vol. 43, no. 4, pp. 333–335, 2015.
Abstract | BibTeX | Tags: *Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male
@article{Guthrie2015,
title = {Emerging data on the incidence of concussion in football practice at all levels of amateur play},
author = {Guthrie, R M},
year = {2015},
date = {2015-01-01},
journal = {Physician \& Sportsmedicine},
volume = {43},
number = {4},
pages = {333--335},
abstract = {There has been increasing concern, particularly in the US, about potential long-term neurological deterioration syndromes seen in the US football players. Recurrent concussions are a potential area of concern. The authors of this paper have used data bases from three levels of amateur US football to identify the rate and risk of concussion injury in both football games and practice at the youth, high school, and college levels. This information is very important initial data around concussion rates at these levels.},
keywords = {*Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Svaldi, D O; Joshi, C; Robinson, M E; Shenk, T E; Abbas, K; Nauman, E A; Leverenz, L J; Talavage, T M
Cerebrovascular reactivity alterations in asymptomatic high school football players Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 80–84, 2015.
Abstract | BibTeX | Tags: *Athletes, *Brain Concussion/pp [Physiopathology], *Brain Injury, *Cerebrovascular Disorders/pp [Physiopathology], *Football/in [Injuries], Adolescent, Chronic/pp [Physiopathology], Humans, RISK assessment, Schools
@article{Svaldi2015,
title = {Cerebrovascular reactivity alterations in asymptomatic high school football players},
author = {Svaldi, D O and Joshi, C and Robinson, M E and Shenk, T E and Abbas, K and Nauman, E A and Leverenz, L J and Talavage, T M},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {80--84},
abstract = {Cerebrovascular reactivity (CVR) is impaired following brain injury, increasing susceptibility to subsequent injury. CVR was tracked in football and non-collision athletes throughout one season. CVR transiently decreased in football athletes during the first half of the season. Results indicate the brain adapts slowly to increases in loading, increasing risk for injury.},
keywords = {*Athletes, *Brain Concussion/pp [Physiopathology], *Brain Injury, *Cerebrovascular Disorders/pp [Physiopathology], *Football/in [Injuries], Adolescent, Chronic/pp [Physiopathology], Humans, RISK assessment, Schools},
pubstate = {published},
tppubtype = {article}
}
Rogers, L A
Let the Kids Play Football! Journal Article
In: North Carolina Medical Journal, vol. 76, no. 4, pp. 272, 2015.
BibTeX | Tags: *Brain Concussion/et [Etiology], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], Adolescent, Child, Humans, UNITED States
@article{Rogers2015b,
title = {Let the Kids Play Football!},
author = {Rogers, L A},
year = {2015},
date = {2015-01-01},
journal = {North Carolina Medical Journal},
volume = {76},
number = {4},
pages = {272},
keywords = {*Brain Concussion/et [Etiology], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], Adolescent, Child, Humans, UNITED States},
pubstate = {published},
tppubtype = {article}
}
Swartz, E E; Broglio, S P; Cook, S B; Cantu, R C; Ferrara, M S; Guskiewicz, K M; Myers, J L
Early Results of a Helmetless-Tackling Intervention to Decrease Head Impacts in Football Players Journal Article
In: Journal of Athletic Training, vol. 50, no. 12, pp. 1219–1222, 2015.
Abstract | BibTeX | Tags: *Craniocerebral Trauma/pc [Prevention & Control], *Football/in [Injuries], *Physical Education and Training/mt [Methods], Acceleration, Head Protective Devices, Humans, Male, Prospective Studies, Universities
@article{Swartz2015,
title = {Early Results of a Helmetless-Tackling Intervention to Decrease Head Impacts in Football Players},
author = {Swartz, E E and Broglio, S P and Cook, S B and Cantu, R C and Ferrara, M S and Guskiewicz, K M and Myers, J L},
year = {2015},
date = {2015-01-01},
journal = {Journal of Athletic Training},
volume = {50},
number = {12},
pages = {1219--1222},
abstract = {OBJECTIVE: To test a helmetless-tackling behavioral intervention for reducing head impacts in National Collegiate Athletic Association Division I football players. DESIGN: Randomized controlled clinical trial. SETTING: Football field. PATIENTS OR OTHER PARTICIPANTS: Fifty collegiate football players (intervention = 25},
keywords = {*Craniocerebral Trauma/pc [Prevention \& Control], *Football/in [Injuries], *Physical Education and Training/mt [Methods], Acceleration, Head Protective Devices, Humans, Male, Prospective Studies, Universities},
pubstate = {published},
tppubtype = {article}
}
Nauman, E A; Breedlove, K M; Breedlove, E L; Talavage, T M; Robinson, M E; Leverenz, L J
Post-Season Neurophysiological Deficits Assessed by ImPACT and fMRI in Athletes Competing in American Football Journal Article
In: Developmental Neuropsychology, vol. 40, no. 2, pp. 85–91, 2015.
Abstract | BibTeX | Tags: *Athletes, *Brain Concussion/pp [Physiopathology], *Football/in [Injuries], *MAGNETIC resonance imaging, Adolescent, Brain Concussion/pa [Pathology], Head, Humans, Male, Neurophysiology, Neuropsychological Tests, Schools, Seasons, Surveys and Questionnaires, UNITED States, Young Adult
@article{Nauman2015,
title = {Post-Season Neurophysiological Deficits Assessed by ImPACT and fMRI in Athletes Competing in American Football},
author = {Nauman, E A and Breedlove, K M and Breedlove, E L and Talavage, T M and Robinson, M E and Leverenz, L J},
year = {2015},
date = {2015-01-01},
journal = {Developmental Neuropsychology},
volume = {40},
number = {2},
pages = {85--91},
abstract = {Neurocognitive assessment, functional magnetic resonance imaging, and head impact monitoring were used to evaluate neurological changes in high school football players throughout competitive seasons. A substantial number of asymptomatic athletes exhibited neurophysiological changes that persisted post-season, with abnormal measures significantly more common in athletes receiving 50 or more hits per week during the season.},
keywords = {*Athletes, *Brain Concussion/pp [Physiopathology], *Football/in [Injuries], *MAGNETIC resonance imaging, Adolescent, Brain Concussion/pa [Pathology], Head, Humans, Male, Neurophysiology, Neuropsychological Tests, Schools, Seasons, Surveys and Questionnaires, UNITED States, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Maroon, J C; Bailes, J; Collins, M; Lovell, M; Mathyssek, C
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Maroon2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Maroon, J C and Bailes, J and Collins, M and Lovell, M and Mathyssek, C},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Orchard, J W
Match of the decade: risk management of concussion versus high-speed collisions in the football codes Journal Article
In: Medical Journal of Australia, vol. 203, no. 7, pp. 281–282, 2015.
BibTeX | Tags: *Athletic Injuries/cl [Classification], *Athletic Injuries/di [Diagnosis], *Brain Concussion/cl [Classification], *Brain Concussion/di [Diagnosis], *Football/in [Injuries], Humans, Injury Severity Score, Male, Risk Factors
@article{Orchard2015,
title = {Match of the decade: risk management of concussion versus high-speed collisions in the football codes},
author = {Orchard, J W},
year = {2015},
date = {2015-01-01},
journal = {Medical Journal of Australia},
volume = {203},
number = {7},
pages = {281--282},
keywords = {*Athletic Injuries/cl [Classification], *Athletic Injuries/di [Diagnosis], *Brain Concussion/cl [Classification], *Brain Concussion/di [Diagnosis], *Football/in [Injuries], Humans, Injury Severity Score, Male, Risk Factors},
pubstate = {published},
tppubtype = {article}
}
Wandling, M W; Guillamondegui, O D
Eliminating the Confusion Surrounding Concussions in Sports Journal Article
In: JAMA, vol. 314, no. 13, pp. 1388–1389, 2015.
BibTeX | Tags: *Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male
@article{Wandling2015,
title = {Eliminating the Confusion Surrounding Concussions in Sports},
author = {Wandling, M W and Guillamondegui, O D},
year = {2015},
date = {2015-01-01},
journal = {JAMA},
volume = {314},
number = {13},
pages = {1388--1389},
keywords = {*Athletic Injuries/ep [Epidemiology], *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Pham, H; Zemek, R
A 15-year-old rugby player with a head injury Journal Article
In: CMAJ Canadian Medical Association Journal, vol. 187, no. 3, pp. 200–202, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Football/in [Injuries], Adolescent, Athletic Injuries/di [Diagnosis], Athletic Injuries/rh [Rehabilitation], Brain Concussion/ra [Radiography], Brain Concussion/rh [Rehabilitation], Brain Concussion/th [Therapy], Female, Glasgow Coma Scale, Humans, Physical Examination, Recovery of Function, Tomography, X-Ray Computed
@article{Pham2015,
title = {A 15-year-old rugby player with a head injury},
author = {Pham, H and Zemek, R},
year = {2015},
date = {2015-01-01},
journal = {CMAJ Canadian Medical Association Journal},
volume = {187},
number = {3},
pages = {200--202},
keywords = {*Brain Concussion/di [Diagnosis], *Football/in [Injuries], Adolescent, Athletic Injuries/di [Diagnosis], Athletic Injuries/rh [Rehabilitation], Brain Concussion/ra [Radiography], Brain Concussion/rh [Rehabilitation], Brain Concussion/th [Therapy], Female, Glasgow Coma Scale, Humans, Physical Examination, Recovery of Function, Tomography, X-Ray Computed},
pubstate = {published},
tppubtype = {article}
}
Andrikopoulos, J
Age of first exposure to football and later-life cognitive impairment in former NFL players Journal Article
In: Neurology, vol. 85, no. 11, pp. 1007, 2015.
BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male
@article{Andrikopoulos2015,
title = {Age of first exposure to football and later-life cognitive impairment in former NFL players},
author = {Andrikopoulos, J},
year = {2015},
date = {2015-01-01},
journal = {Neurology},
volume = {85},
number = {11},
pages = {1007},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/ep [Epidemiology], *Cognition Disorders/di [Diagnosis], *Cognition Disorders/ep [Epidemiology], *Football/in [Injuries], *Neuropsychological Tests, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Freitag, A; Kirkwood, G; Scharer, S; Ofori-Asenso, R; Pollock, A M
Systematic review of rugby injuries in children and adolescents under 21 years Journal Article
In: British Journal of Sports Medicine, vol. 49, no. 8, pp. 511–519, 2015.
Abstract | BibTeX | Tags: *Football/in [Injuries], Absenteeism, Adolescent, Athletic Injuries/ep [Epidemiology], Brain Concussion/ep [Epidemiology], Child, Contusions/ep [Epidemiology], Craniocerebral Trauma/ep [Epidemiology], Dislocations/ep [Epidemiology], Extremities/in [Injuries], Female, Hematoma/ep [Epidemiology], Humans, Incidence, Lacerations/ep [Epidemiology], Male, Neck Injuries/ep [Epidemiology], RISK assessment, Sprains and Strains/ep [Epidemiology], Torso/in [Injuries], Young Adult
@article{Freitag2015a,
title = {Systematic review of rugby injuries in children and adolescents under 21 years},
author = {Freitag, A and Kirkwood, G and Scharer, S and Ofori-Asenso, R and Pollock, A M},
year = {2015},
date = {2015-01-01},
journal = {British Journal of Sports Medicine},
volume = {49},
number = {8},
pages = {511--519},
abstract = {A systematic review of rugby union and league injuries among players under the age of 21 years was carried out to calculate probabilities of match injury for a player over a season and a pooled estimate of match injury incidence where studies were sufficiently similar. The probability of a player being injured over a season ranged from 6% to 90% for rugby union and 68% to 96% for rugby league. The pooled injury incidence estimate for rugby union was 26.7/1000 player-hours for injuries irrespective of need for medical attention or time-loss and 10.3/1000 player-hours for injuries requiring at least 7 days absence from games; equivalent to a 28.4% and 12.1% risk of being injured over a season. Study heterogeneity contributed to a wide variation in injury incidence. Public injury surveillance and prevention systems have been successful in reducing injury rates in other countries. No such system exists in the UK. Copyright Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.},
keywords = {*Football/in [Injuries], Absenteeism, Adolescent, Athletic Injuries/ep [Epidemiology], Brain Concussion/ep [Epidemiology], Child, Contusions/ep [Epidemiology], Craniocerebral Trauma/ep [Epidemiology], Dislocations/ep [Epidemiology], Extremities/in [Injuries], Female, Hematoma/ep [Epidemiology], Humans, Incidence, Lacerations/ep [Epidemiology], Male, Neck Injuries/ep [Epidemiology], RISK assessment, Sprains and Strains/ep [Epidemiology], Torso/in [Injuries], Young Adult},
pubstate = {published},
tppubtype = {article}
}
Wood, H
Traumatic brain injury: Cerebral blood flow is linked to sports-related concussion outcomes Journal Article
In: Nature Reviews Neurology, vol. 11, no. 4, pp. 185, 2015.
BibTeX | Tags: *Brain Concussion/pp [Physiopathology], *Cerebral Cortex, *Cerebrovascular Circulation/ph [Physiology], *Football/in [Injuries], *Recovery of Function/ph [Physiology], Humans, Male
@article{Wood2015a,
title = {Traumatic brain injury: Cerebral blood flow is linked to sports-related concussion outcomes},
author = {Wood, H},
year = {2015},
date = {2015-01-01},
journal = {Nature Reviews Neurology},
volume = {11},
number = {4},
pages = {185},
keywords = {*Brain Concussion/pp [Physiopathology], *Cerebral Cortex, *Cerebrovascular Circulation/ph [Physiology], *Football/in [Injuries], *Recovery of Function/ph [Physiology], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Myer, G D; Smith, D; Foss, K D; DiCesare, C A; Kiefer, A W; Kushner, A M; Thomas, S M; Sucharew, H; Khoury, J C
Response Journal Article
In: Journal of Orthopaedic & Sports Physical Therapy, vol. 44, no. 6, pp. 459–460, 2014.
BibTeX | Tags: *Altitude, *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male
@article{Myer2014a,
title = {Response},
author = {Myer, G D and Smith, D and Foss, K D and DiCesare, C A and Kiefer, A W and Kushner, A M and Thomas, S M and Sucharew, H and Khoury, J C},
year = {2014},
date = {2014-01-01},
journal = {Journal of Orthopaedic \& Sports Physical Therapy},
volume = {44},
number = {6},
pages = {459--460},
keywords = {*Altitude, *Brain Concussion/ep [Epidemiology], *Football/in [Injuries], Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Rowson, S; Duma, S M; Greenwald, R M; Beckwith, J G; Guskiewicz, K M; Crisco, J J; Wilcox, B J; McAllister, T W; Maerlender, A C; Broglio, S P; Schnebel, B; Brolinson, P G
Response Journal Article
In: Journal of Neurosurgery, vol. 121, no. 2, pp. 492–493, 2014.
BibTeX | Tags: *Athletic Injuries/pc [Prevention & Control], *Brain Concussion/pc [Prevention & Control], *Football/in [Injuries], *Head Protective Devices, Humans, Male
@article{Rowson2014a,
title = {Response},
author = {Rowson, S and Duma, S M and Greenwald, R M and Beckwith, J G and Guskiewicz, K M and Crisco, J J and Wilcox, B J and McAllister, T W and Maerlender, A C and Broglio, S P and Schnebel, B and Brolinson, P G},
year = {2014},
date = {2014-01-01},
journal = {Journal of Neurosurgery},
volume = {121},
number = {2},
pages = {492--493},
keywords = {*Athletic Injuries/pc [Prevention \& Control], *Brain Concussion/pc [Prevention \& Control], *Football/in [Injuries], *Head Protective Devices, Humans, Male},
pubstate = {published},
tppubtype = {article}
}
Beckwith, J G; Greenwald, R M; Chu, J J; Crisco, J J; Rowson, S; Duma, S M; Broglio, S P; McAllister, T W; Guskiewicz, K M; Mihalik, J P; Anderson, S; Schnebel, B; Brolinson, P G; Collins, M W
Timing of concussion diagnosis is related to head impact exposure prior to injury Journal Article
In: Medicine & Science in Sports & Exercise, vol. 45, no. 4, pp. 747–754, 2013.
Abstract | BibTeX | Tags: *Brain Concussion/di [Diagnosis], *Brain Concussion/et [Etiology], *Delayed Diagnosis, *Football/in [Injuries], *HEAD injuries, Adolescent, Closed/ep [Epidemiology], ENVIRONMENTAL exposure, Head Protective Devices, Humans, Male, Telemetry/is [Instrumentation], Time Factors, Young Adult
@article{Beckwith2013a,
title = {Timing of concussion diagnosis is related to head impact exposure prior to injury},
author = {Beckwith, J G and Greenwald, R M and Chu, J J and Crisco, J J and Rowson, S and Duma, S M and Broglio, S P and McAllister, T W and Guskiewicz, K M and Mihalik, J P and Anderson, S and Schnebel, B and Brolinson, P G and Collins, M W},
year = {2013},
date = {2013-01-01},
journal = {Medicine \& Science in Sports \& Exercise},
volume = {45},
number = {4},
pages = {747--754},
abstract = {PURPOSE: Concussions are commonly undiagnosed in an athletic environment because the postinjury signs and symptoms may be mild, masked by the subject, or unrecognized. This study compares measures of head impact frequency, location, and kinematic response before cases of immediate and delayed concussion diagnosis. METHODS: Football players from eight collegiate and six high school teams wore instrumented helmets during play (n = 1208), of which 95 were diagnosed with concussion (105 total cases). Acceleration data recorded by the instrumented helmets were reduced to five kinematic metrics: peak linear and rotational acceleration, Gadd severity index, head injury criterion, and change in head velocity (DELTAv). In addition, each impact was assigned to one of four general location regions (front, back, side, and top), and the number of impacts sustained before injury was calculated over two periods (1 and 7 days). RESULTS: All head kinematic measures associated with injury, except peak rotational acceleration (P = 0.284), were significantly higher for cases of immediate diagnosis than delayed diagnosis (P \< 0.05). Players with delayed diagnosis sustained a significantly higher number of head impacts on the day of injury (32.9 +/- 24.9, P \< 0.001) and within 7 d of injury (69.7 +/- 43.3},
keywords = {*Brain Concussion/di [Diagnosis], *Brain Concussion/et [Etiology], *Delayed Diagnosis, *Football/in [Injuries], *HEAD injuries, Adolescent, Closed/ep [Epidemiology], ENVIRONMENTAL exposure, Head Protective Devices, Humans, Male, Telemetry/is [Instrumentation], Time Factors, Young Adult},
pubstate = {published},
tppubtype = {article}
}
Thornton, A E; Cox, D N; Whitfield, K; Fouladi, R T
Cumulative concussion exposure in rugby players: neurocognitive and symptomatic outcomes Journal Article
In: Journal of Clinical & Experimental Neuropsychology, vol. 30, no. 4, pp. 398–409, 2008.
Abstract | BibTeX | Tags: *Brain Concussion/co [Complications], *COGNITION, *Cognition Disorders/et [Etiology], *Football/in [Injuries], adult, Age Factors, aged, Brain Concussion/di [Diagnosis], Female, Humans, Male, middle aged, Neuropsychological Tests, Predictive Value of Tests, REGRESSION analysis, Surveys and Questionnaires, Trauma Severity Indices
@article{Thornton2008a,
title = {Cumulative concussion exposure in rugby players: neurocognitive and symptomatic outcomes},
author = {Thornton, A E and Cox, D N and Whitfield, K and Fouladi, R T},
year = {2008},
date = {2008-01-01},
journal = {Journal of Clinical \& Experimental Neuropsychology},
volume = {30},
number = {4},
pages = {398--409},
abstract = {A total of 111 rugby players underwent comprehensive testing to determine the impact of self-reported concussion exposure. Reliable estimates of concussion exposure were associated with an increase in postconcussion symptoms (PCS), but not diminished neurocognitive functioning. Importantly, the effects of concussion exposure on PCS varied as a function of player status. More specifically, extent of concussion exposure was associated with increased memory complaints and overall PCS endorsements in a dose-dependent manner for retired and older recreational players, but not for those who were younger and playing at more competitive levels. Future work should systematically evaluate the constituent participant factors that may influence differential concussion outcomes.},
keywords = {*Brain Concussion/co [Complications], *COGNITION, *Cognition Disorders/et [Etiology], *Football/in [Injuries], adult, Age Factors, aged, Brain Concussion/di [Diagnosis], Female, Humans, Male, middle aged, Neuropsychological Tests, Predictive Value of Tests, REGRESSION analysis, Surveys and Questionnaires, Trauma Severity Indices},
pubstate = {published},
tppubtype = {article}
}